10 results about "Drusen" patented technology

Methods of treating age-related macular degeneration (AMD) may include the administration of amphipathic, ATP binding cassette transporter membrane agonists to reduce the amount of drusen in the subject in need thereof. These methods may be particularly useful for treatment of intermediate AMD.

A system includes a vision screening device having at least one sensor. The system also includes a controller operably connected to the at least one sensor. The controller is configured to cause the at least one sensor to obtain an image of an eye, and to identify a region of interest associated with a macula of the eye. The controller is also configured to identify drusen disposed proximate the macula, and to generate an augmented image of the eye. The augmented image includes a component indicating the drusen.

The present invention discloses an OCT image stratification and lesion semantic segmentation method, device and storage medium. The method comprises: obtaining each BScan two-dimensional slice image data of OCT of one eye of a patient to be examined; inputting the slice image data one by one into a pre-trained first-stage convolutional neural network to obtain the first-stage stratification, optic disc area, and semantic segmentation prediction results of the macula fovea area; making a "region of interest" according to the obtained first-stage stratification, optic disc area, and semantic segmentation prediction results of the macula fovea area; obtaining a data map of the "region of interest"; inputting the data map of the "region of interest" into a second-stage convolutional neural network to obtain the second-stage stratification, drusen, pigment epithelial detachment, and semantic segmentation prediction results of choroidal neovascularization lesions. The present invention increases the proportion of lesion pixels to total pixels and reduces the learning difficulty of small-area positive lesions such as drusen.

A system includes a vision screening device having at least one sensor. The system also includes a controller operably connected to the at least one sensor. The controller is configured to cause the at least one sensor to obtain an image of an eye, and to identify a region of interest associated with a macula of the eye. The controller is also configured to identify drusen disposed proximate the macula, and to generate an augmented image of the eye. The augmented image includes a component indicating the drusen.

The invention relates to the technical field of optical coherence tomography (OCT), and particularly discloses a method for compensating backscattering of a soft glass film of a retina layer. An SS-OCT imaging system is used for collecting an image, an original OCT image is obtained, a retinal pigment epithelium (RPE) layer and a Drusen area below the RPE layer are obtained through image enhancement and noise filtering, an initial optical attenuation coefficient (OAC) and an initial backscattering coefficient alpha of the RPE layer and the Drusen area are calculated through a local depth resolution (LDR) algorithm, backscattering compensation is carried out on the Drusen area, and therefore the RPE layer and the Drusen area are obtained. The backscattering coefficient of the Drusen region is matched with the RPE layer, and the OAC of the compensated RPE layer and the Drusen region is calculated by using a local depth resolution (LDR) algorithm. According to the method, the calculation precision of the optical attenuation coefficient can be remarkably improved, and finally more reliable data support is provided for AMD diagnosis.

Medical equipment for detecting Drusen

Provided are formulations and methods for treating patients having AMD, by inhibiting formation or growth of drusen, and / or reducing number and / or size of drusen, while maintaining or restoring ellipsoid zone area in a human eye.

Provided are formulations and methods for treating drusen and / or AMD, such that the risk of vitreous flare and lens opacity or lens haziness, e.g., cataract formation, is reduced or substantially eliminated.

The present invention relates to superoxide dismutase and a use thereof for preventing or treating dry age-related macular degeneration. More specifically, the present invention relates to a pharmaceutical composition or a therapeutic method for prevention or treatment of dry macular degeneration. The composition and method according to the present invention can be effectively used to prevent or treat dry macular degeneration by reducing or preventing drusen formation and / or drusenoid lesions.