To provide specific N4-hydroxycytidine derivatives, pharmaceutical compositions, and related methods. [Solution] In certain embodiments, this disclosure relates to the treatment or prevention of viral infections such as Eastern
equine encephalitis, Western
equine encephalitis, and Venezuelan
equine encephalitis (EEE, WEE, and VEE, respectively),
Chikungunya fever (CHIK), Ebola, influenza, RSV, and
Zika virus infection, by the compounds disclosed. In certain embodiments, this disclosure intends to provide derivatives of the compounds disclosed herein, such as compounds containing one or more of the same or different substituents.