2 results about "Immunoglobulin class" patented technology

The invention discloses a blood group reagent quality control kit and application thereof, the blood group reagent quality control kit comprises a plurality of independently subpackaged composite quality control products, and each quality control product simultaneously comprises quality control red blood cells with known antigen spectra and quality control plasma with known antibody spectra; the quality control red blood cells are human red blood cells with known ABO blood type, RhD blood type and Rh haplotype; the quality control plasma contains blood group antibodies with known specificity and immune globulin types, and the blood group antibodies comprise IgM antibodies and / or IgG antibodies. The invention also discloses application of the blood group reagent quality control kit in indoor quality control of blood group serology detection and an indoor quality control method of blood group serology detection. The kit provided by the invention can realize integrated and efficient detection, and synchronously complete indoor quality control of a plurality of core items such as blood type identification, antibody screening, cross matching of blood and the like.

Method and kit for elimination of rheumatoid factor interference in immunoassays The invention relates to an in vitro method of reducing and / or eliminating unwanted detection of an IgG antibody in an immunoassay on a biological sample containing rheumatoid factor (RF), the method comprising contacting said biological sample with a RF interference-reducing protein comprising an amino acid sequence of SEQ ID NO. 1, 2 or 3, and capable of binding to the Fc domain of IgG antibodies. Also disclosed is an in vitro method for detecting antibodies specific to an antigen in a biological sample that belong to one or more immunoglobulin classes other than IgG, which makes use of the aforementioned RF interference-reducing protein. There are further described a kit for carrying out the method of the invention and the use in said method of a fusion protein comprising said RF interference-reducing protein linked to a fusion partner.