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234 results about "LBP - low back pain" patented technology

Low back pain (LBP) is a common disorder involving the muscles, nerves, and bones of the back. Pain can vary from a dull constant ache to a sudden sharp feeling. Low back pain may be classified by duration as acute (pain lasting less than 6 weeks), sub-chronic (6 to 12 weeks), or chronic (more than 12 weeks).

Cytokine antagonists for neurological and neuropsychiatric disorders

Methods for treating neurological or neuropsychiatric diseases or disorders in humans by administering to the human a therapeutically effective dose of specific biologics are presented. The biologics of consideration include antagonists of tumor necrosis factor or of interleukin-1. The administration of these biologics is performed by specific methods, most, but not all of which fall into the category of anatomically localized administration designed for perispinal use. Anatomically localized administration involving perispinal use includes, but is not limited to the subcutaneous, intramuscular, interspinous, epidural, peridural, parenteral or intrathecal routes. Additonally, intranasal administration is discussed as a method to provide therapeutic benefit. The clinical conditions of consideration include, but are not limited to the following: diseases of the brain, including neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease; migraine headache; spinal radiculopathy associated with intervertebral disc herniation, post-herpetic neuralgia, reflex sympathethic dystrophy, neuropathic pain, vertebral disc disease, low back pain, amyotrophic lateral sclerosis, chronic fatigue syndrome; and neuropsychiatric diseases, including bipolar affective disorder, anorexia nervosa, nicotine withdrawal, narcotic addiction, alcohol withdrawl, postpartum depression, and schizoaffective illness.
Owner:TACT IP

Heat Generating Pad And Method Of Use Of The Same

To provide a heat generating pad which is able to relax symptoms such as stiff shoulder, low-back pain, muscular fatigue, menstrual pain, a symptom of poor circulation and in particular, can be suitably used for relaxation of a symptom of menstrual pain and a method of use of the same. A heat generating pad in which a heat generating composition molded body resulting from molding a moldable heat generating composition containing surplus water as a connecting substance is interposed between packaging materials and the periphery of the heat generating composition molded body is heat sealed, which is characterized in that the packaging materials are constituted of a substrate and a covering material; that the substrate is substantially planar and does not contain an accommodating pocket; that the heat sealing forms a sectioned part as formed in a striped form, and plural sectional exothermic parts as sectioned by the heat sealing are provided via the sectioned part; that the moldable heat generating composition has a water content of from 1 to 60% by weight, contains, as essential components, a flocculant aid , a drybinding agent, a flocculant, adhesive binder, an iron powder, a carbon component, a reaction accelerator and water, does not contain, a thickener and an excipient, contains the surplus water so as to have a water mobility value of from 0.01 to 20, with the water in the moldable heat generating composition not functioning as a barrier layer, and is capable of causing an exothermic reaction upon contact with air; that the heat generating pad contains a region having a ratio of bending resistance in the orthogonal directions of 2 or more on the surface thereof orthogonal to the thickness direction of the heat generating pad; that at least a part of the heat generating pad has air permeability; and that the heat generating pad has a fixing measure on at least a part of the exposed surface thereof.
Owner:MYCOAL PRODS CORP

Mr spectroscopy system and method for diagnosing painful and non-painful intervertebral discs

An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing & diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio (SNR) by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra along regions associated with multiple chemicals that have been correlated to painful vs. non-painful discs. A diagnostic display provides a scaled, color coded legend and indication of results for each disc analyzed as an overlay onto a mid-sagittal T2-weighted MRI image of the lumbar spine for the patient being diagnosed. Clinical application of the embodiments provides a non-invasive, objective, pain-free, reliable approach for diagnosing painful vs. non-painful discs by simply extending and enhancing the utility of otherwise standard MRI exams of the lumbar spine.
Owner:ACLARION INC +1

Prophylactic/ameliorating agent for adult diseases comprising 5-aminolevulinic acid, derivative of 5-aminolevulinic acid, or salt of 5-aminolevulinic acid or the derivative or 5-aminolevulinic acid as active ingredient

ActiveUS20110196033A1Ameliorate and prevent adult diseaseImprove basal metabolismHeavy metal active ingredientsBiocideImpaired liver functionDisease
It is to provide a pharmaceutical composition which is different from an existing therapeutic agent of an adult disease, of a biochemical reaction-inhibiting type, and which action mechanism is to improve the basal metabolism, wherein the composition has no side effects, and does not generate drug resistance against adult disease; and a method for preventing/treating an adult disease by using the same. It is to provide a composition for preventing/ameliorating an adult disease such as metabolic syndrome, diabetes, hyperlipidemia, hypertension, impaired liver function, renal failure, adiposity, erectile dysfunction, menopausal disorder, shoulder discomfort, and low back pain, comprising 5-aminolevulinic acid (ALA), its derivative, or salt thereof, preferably comprising ALA, its derivative, or salt thereof, and an iron compound such as sodium ferrous citrate, iron sodium citrate and iron ammonium citrate; a food or food material for preventing/ameliorating an adult disease comprising the composition; and a method for using the composition for preparing an agent for preventing/ameliorating an adult disease.
Owner:SBI PHARMA CO LTD

Heat Generating Body, Heat Insulating Method Using The Same And Packaging Material For Die Molding Heat Generation

To provide a heat generating body which is able to relax symptoms such as stiff shoulder, low-back pain, muscular fatigue, menstrual pain, a symptom of poor circulation and in particular, can be suitably used for relaxation of a symptom of menstrual pain.
A heat generating body wherein a heat generating composition molded body resulting from molding a moldable heat generating composition containing surplus water as a connecting substance is interposed between packaging materials and the periphery of the heat generating composition molded body is heat sealed, which is characterized in that the packaging materials are each constituted of a substrate and a covering material; that the substrate is substantially planar and does not have an accommodating pocket; that the packaging materials each has a bending resistance of not more than 100 mm; that the packaging materials are each a non-elastic body at least at a temperature between 25° C. and 60° C., has a breaking strength of 500 g/mm2 or more at 25° C. and has a breaking elongation of 30% or more at 90° C.; that the moldable heat generating composition contains, as essential components, an iron powder, a carbon component, a reaction accelerator and water, has a water content of from 1 to 60% by weight, does not contain a flocculent aid, a flocculant, an agglomeration aid, a dry binder, a dry binding agent, a dry binding material, a sticky raw material, a thickener and an excipient, contains the surplus water so as to have a water mobility value of from 0.01 to 20, has moldability due to the surplus water, with the water in the moldable heat generating composition not functioning as a barrier layer, and is capable of causing an exothermic reaction upon contact with air; that plural sectional exothermic parts as divided by a sectioned part which is formed by heat sealing are provided; that the heat generating body contains a region having a ratio of bending resistance in the orthogonal directions of 2 or more on the surface thereof orthogonal to the thickness direction of the heat generating body; that at least a part of the heat generating body has permeability to air; and that the heat generating body has a fixing measure on at least a part of the exposed surface thereof.
Owner:S T CORP
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