30results about How to "Compromise ability" patented technology

<heading lvl="0">Abstract of Disclosure< / heading> A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue, particularly fetal or neo-natal tissue, to chemical and mechanical processing. The process includes, but is not limited t, harvesting the tissue, optionally extracting growth and differentiation factors from the tissue, inactivating infective agents of the tissue, mechanically expressig undesirable components frm the tissue, delipidizing the tissue, washing the tissue, optionally drying the tissue, and optionally cross-linking the tissue not necessarily in the order described. The resulting product, EBM, is characterized by its microbial, fungal, viral and prion inactivated state. EBM is storng, bioremodelable, drapable and does not undergo calicification. EBM supplants previous inventions because of its unique method of preparation and broad applicability in tissue reengineering

A packaging sleeve for retaining a plurality of individually packaged products includes a first sidewall having a first opening that partially receives a first product of the plurality of individually packaged products, as well as a reinforcing biasing beam that exhibits a spring action to bias the first product into the first opening by applying a force to the first product in a direction toward the first opening. The biasing beam includes a first wall and a second wall, with the first wall of the biasing beam contacting and biasing the first product, and the second wall of the biasing beam contacting a second product and biasing the second product into a second opening formed in the sleeve. The biasing beam is convertible between a fully compressed state and a fully expanded state, with the biasing beam being biased to the fully expanded state.

Methods and apparatus are provided for managing data communications between hosts (9) of a switched Ethernet network (8). Hosts (9) are assigned to logical groups of hosts such that the hosts participating in a data communication are assigned to the same group. In a switch (1) of the network, each group is associated with a service class indicative of requirements for forwarding data across the switch (1) for data communications between hosts (9) in that group. Data received by the switch (1) is forwarded across the switch in a manner dependent on the service class of the group to which hosts (9) participating in the data communication are assigned. In the switch (1), data communications between hosts (9) in one or more of said groups are disabled when required to satisfy the forwarding requirements for at least one said service class.

The invention relates to the modification of human Factor VIII (FVIII) to result in FVIII proteins that are substantially non-immunogenic or less immunogenic than any non-modified counterpart when used in vivo. The invention relates furthermore to T-cell epitope peptides derived from said non-modified protein by means of which it is possible to create modified FVIII variants with reduced immunogenicity.

An annular surround for a loudspeaker cone wherein a radial cross-section of the surround varies around the circumferential extent of the surround, so as to accommodate peripheral expansion or contraction of the surround by bending. Thus a trough shaped cross-section of the surround may vary sinusoidally with angle around the polar axis of the surround between a semicircular and semielliptical cross-section. The trough section may bland to an adjacent portion of the surround by a fillet which also varies sinusoidally in cross-section in phase with the variation of the trough.

A fuel control approach that compensates for time delays to increase exhaust gas sensor feedback response speed.

The invention relates to the identification of epitopes for T-cells in human EPO as well as T-cell epitope peptides derived from EPO by means of which it is possible to create novel modified EPO variants with reduced immunogenicity.

A food package is provided that includes a compartment in which food items are carried and a holder portion which allows a user to place the food item therein with the food item held in a stationary position. The food holder can serve as a staging area for combining the food item with other food items or can be used as a placement location for a partially eaten food item. In the preferred multicompartment package, an improved back card construction is also disclosed.

A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue, particularly fetal or neo-natal tissue, to chemical and mechanical processing. The process includes, but is not limited to, harvesting the tissue, optionally extracting growth and differentiation factors from the tissue, inactivating infective agents of the tissue, mechanically expressing undesirable components from the tissue, delipidizing the tissue, washing the tissue, optionally drying the tissue, optionally cross-linking the tissue not necessarily in the order described. The resulting product, EBM, is characterized by its microbial, fungal, viral and prion inactivated state. EBM is strong, bioremodelable, drapable and does not undergo calcification. EBM supplants previous inventions because of its unique method of preparation and broad applicability in tissue reengineering.

A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue to chemical and mechanical processing. In addition to skin tissue, another source of EBM is a blood vessel. EBM may be used for hernia repair, colon, rectal, vaginal and or urethral prolapse treatment; pelvic floor reconstruction; muscle flap reinforcement; lung tissue support; rotator cuff repair or replacement; periosteum replacement; dura repair; pericardial membrane repair; soft tissue augmentation; intervertebral disk repair; and periodontal repair. EBM may also be used as a urethral sling, laminectomy barrier or spinal fusion device.

An all in the head surface cleaning apparatus may have a surface cleaning head including a front end, a rear end, first and second laterally opposed sidewalls. The surface cleaning head may include a cyclone assembly comprising a cyclone chamber and a dirt collection chamber. The cyclone chamber may have a longitudinal cyclone axis, a cyclone assembly air inlet port and a cyclone assembly air outlet port. The cyclone assembly may be moveable from a cleaning position to a cyclone assembly removal position. The surface cleaning head may include a biasing member biasing the cyclone assembly away from the cleaning position, and a suction motor having a suction motor air inlet and a suction motor axis. The apparatus may include an upper portion moveably mounted to the surface cleaning head between a storage position and a floor cleaning position, the upper portion comprising a drive handle.

A fuel control approach that compensates for time delays to increase exhaust gas sensor feedback response speed.

Metal cable having two layers of construction 4+N comprising an inner layer C1 of 4 wires of diameter d1 wound together in a helix at a pitch p1, this layer C1 itself being surrounded by an outer layer C2 of N wires of diameter d2 wound together in a helix at a pitch p2, characterized in that said cable furthermore has the following characteristics (d1, d2, p1 and p2 in mm):0.25<d1<0.40;0.25<d2<0.40;3.5<p1<7<p2<14.Such a cable, of preferred construction 4+9, is in particular usable for reinforcing tires, in particular as an anchoring means for a carcass reinforcement of a tire without a solid bead wire.

The invention relates to the modification of bryodin 1 to result in bryodin 1 proteins that are substantially non-immunogenic or less immunogenic than any non-modified counterpart when used in vivo. The invention relates furthermore to T-cell epitope peptides derived from said nonmodified protein by means of which it is possible to create modified bryodin 1 variants with reduced immunogenicity.

The present invention is directed to a topical ophthalmic composition for a liquid comprised of clear colloidal polar nanolipids delivered in submicron sized particles (Nanopids™), aqueous colloidal lubricants, aqueous polymers, emulsifies, and a unique stabilizing buffer system, which undergoes a liquid-gel phase transition in the eye. Said composition is designed to deliver advanced eye lubricants, protect the three (3) layers of corneal film from dryness, and provide a unique system of Dry Eye treatment that addresses and treats all three layers of corneal tear film. Said composition is further designed to provide a superior delivery system of various Active Pharmaceutical Ingredients (APIs), and / or anti-infective / antibiotic / anti-fungal agents, accepted as safe and efficacious for ophthalmic use.

Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.

Tire comprising a crown surmounted by a tread, a crown reinforcement, two sidewalls and two beads, a carcass reinforcement passing into the two sidewalls and anchored by means for anchoring in the two beads, said anchoring means comprising, in at least one bead, a circumferential alignment of at least one anchoring reinforcing member oriented circumferentially and cooperating with a rubber composition referred to as ‘anchoring rubber’; this tire is characterized in that this anchoring reinforcing member is a metal cable having two layers of construction M+N comprising an inner layer C1 of M wires of diameter d1 wound together in a helix at a pitch p1, this layer C1 itself being surrounded by an outer layer C2 of N wires of diameter d2 wound together in a helix at a pitch p2, this anchoring cable furthermore having the following characteristics (d1, d2, p1 and p2 in mm):2≦M≦4M+3≦N≦M+70.25<d1<0.40;0.25<d2<0.40;3.5<p1<7<p2<14.The invention also relates to a metal / rubber composite comprising the above two-layered metal cable associated with a rubber matrix of high rigidity, having, in the vulcanized state, a secant tensile modulus at 10% elongation which is greater than 20 MPa.

A packaging sleeve for retaining a plurality of individually packaged products includes a first sidewall having a first opening that partially receives a first product of the plurality of individually packaged products, as well as a reinforcing biasing beam that exhibits a spring action to bias the first product into the first opening by applying a force to the first product in a direction toward the first opening. The biasing beam includes a first wall and a second wall, with the first wall of the biasing beam contacting and biasing the first product, and the second wall of the biasing beam contacting a second product and biasing the second product into a second opening formed in the sleeve. The biasing beam is convertible between a fully compressed state and a fully expanded state, with the biasing beam being biased to the fully expanded state.

Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.

The present disclosure relates to methods for the treatment of cancers. In particular, the disclosure provides methods for treatment of cancer by administering a Raf inhibitor in combination with a taxane. The present disclosure relates to methods of treating a subject suffering from cancer, comprising administering to the subject: (i) a Raf kinase inhibitor or a pharmaceutically acceptable salt thereof; and (ii) a taxane or a pharmaceutically acceptable salt thereof; the amount of the Raf kinase inhibitor and taxane or a pharmaceutically acceptable salt thereof is such that the combination thereof is therapeutically effective in the treatment of the cancer.

A compact field spectrograph is described that provides a resolution of 500 or more with no entrance aperture, providing for substantial gain in light throughput, ideal for viewing multiple distant objects with or without telescopic aid, and providing the ability to observe and distinguish a multiplex of objects simultaneously, even if in motion, with minimal or no mechanical tracking required. Spectra may be viewed directly with the unaided eye, or photographed with common consumer cameras.

The invention is directed toward techniques for creating molded substrates for use in various different data storage media. The molded substrates have improved thickness profiles that can improve media quality, and in some cases facilitate higher data storage densities. In many cases, the improved thickness profile is a thickness profile that has improved flatness. Mechanical flatness or optical flatness can be achieved. In particular, optical flatness is desirable for substrates used in holographic data storage media having a sandwiched construction.

Compounds, compositions and methods for improving one or more agronomic characteristics of desired crop plants are described herein. The compounds include oxazoles, oxadiazoles and thiadiazoles.

Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.

The present disclosure relates to methods for the treatment of cancers. In particular, the disclosure provides methods for treatment of cancer by administering a Raf inhibitor in combination with a taxane. The present disclosure relates to methods of treating a subject suffering from cancer, comprising administering to the subject: (i) a Raf kinase inhibitor or a pharmaceutically acceptable salt thereof; and (ii) a taxane or a pharmaceutically acceptable salt thereof; the amount of the Raf kinase inhibitor and taxane or a pharmaceutically acceptable salt thereof is such that the combination thereof is therapeutically effective in the treatment of the cancer.

Doses of cosmetic fluid dispensed from a roll-on dispenser can fluctuate significantly between successive applications. This problem can be alleviated by perturbing flow within the roll-on housing, such as air flow, by forming flow perturbators on the interior side-wall of the housing. These perturbators can alternatively or additionally comprise lateral beads or notching an interior sealing ring. The dispenser housing preferably also includes a spider normally located between the roller and the bottle interior, and preferably a resilient spider having an facing surface parallel with the roller that can control the depth of liquid film adhering to the roller, which when the roller is a ball means a concave upper face of similar radius of curvature to that of the ball.