The invention relates to an RFID based intelligent logistics managing system, which belongs to the field of logistics management, and used for managing logistics information of cargoes with RFID tags. The logistics managing system comprises a logistics control system, a storage system arranged in a warehouse and a vehicle-mounted mobile module, wherein the logistics control system is connected with the storage system and the vehicle-mounted mobile module via a communication network to realize commutation between the logistics control system and the storage system or the vehicle-mounted mobile module, each of the storage system and the vehicle-mounted storage system is equipped with an RFID reader, the RFID readers read information of the RFID tags, and the RFID information is transmitted to the logistics control system. According to the RFID based intelligent logistics managing system, logistics information can be managed in a highly-efficient, automatic, informationized, networked, intelligent and flexible manner.