The invention discloses a multi-terminal fusion territorial resource mobile government affair system based on a heterogeneous network, which mainly relates to the technical field of government affairsystems and comprises an overall architecture module and a security design module, wherein the overall architecture module comprises a mobile office unit, a mobile terminal application, a mobile database, a mobile application server, mobile application software and a mobile configuration management workstation, and the security design module comprises a terminal access security unit, a storage security unit, a transmission security unit, an operation security unit and a mechanism security unit. According to the invention, the unified territorial resource mobile government affair platform of the mobile terminal and the PC terminal is applied as a whole, seamless connection between a territorial resource bureau mobile office application and a government affair system application is realized,and integrated application of the business approval system at the mobile terminal and the PC terminal is realized; and based on a mobile wireless network, high collaborative application with an e-government affair system is realized, and dual expansion and extension of territorial office and government affair application in time and space are completed.