The invention discloses a method for optimizing an integrated circuit of an analog operational amplifier. The method has the advantages that according to the principle and requirement of an analog integrated circuit to be designed, the method can automatically design technical parameters and circuit parameters free from design parameters and the number of optimized targets by applying an intelligent optimized searching method of a Q-deviant immune network, can automatically search and find the optimal technical parameters and circuit parameters meeting the requirements of analog circuit performance indexes in a range of set values, namely meeting the requirements of high direct current gain, unit gain bandwidth, conversion velocity and low power consumption, and provides good foundation and accordance for high-performance analog integrated circuit technological design. Furthermore, the method is applicable to various analog circuit designs, is easy for transplanting, and has wide applicability and high universality.