The invention discloses an image similarity determination method and device, equipment, a medium and a product, and the method comprises the steps: obtaining m first theme colors corresponding to a first image and n second theme colors corresponding to a second image, taking the minimum matching distance as a target, carrying out the matching of the m first theme colors and the n second theme colors, and obtaining k color pairs; each color pair comprises a first theme color and a second theme color, different color pairs comprise different first theme colors, and different color pairs comprise different second theme colors. Wherein the matching distance is used for representing the sum of the color distances corresponding to the k color pairs. And finally, determining the image similarity between the first image and the second image according to the shortest matching distance. Visibly, a mode of matching based on theme colors is provided, the similarity between the images is evaluated from the visual level, the similarity between the images can be reflected more visually, manual calibration of image pairs, sample labels and the like is not needed any more, and cost is saved.