The invention relates to a method for cooperatively controlling an air pressure and regenerative brake of a hybrid electric bus, which belongs to the technical field of new-energy vehicles. The method comprises the following steps of: firstly, collecting a current air pressure brake force, a brake pedal travel, a brake pedal travel speed, battery information, motor information and vehicle state information of a hybrid electric bus; secondly, distributing the air pressure brake force and a motor brake force by utilizing a regenerative brake force distribution algorithm; thirdly, cooperatively controlling regenerative brake and an ABS (Antilock Brake System) by utilizing a regenerative brake and ABS cooperative control algorithm; and fourthly, compensating and controlling the air pressure brake force by utilizing an air pressure brake force compensation control algorithm. By utilizing the invention, part resources of the common air pressure brake system and the regenerative brake system of the hybrid electric bus can be fully utilized, the brake energy can be recycled to the maximum extent, the economical efficiency of the entire bus is enhanced, and wheels can be prevented from locking so that the brake safety of the entire bus is improved.