The invention provides a SAGD low-physical property interlayer acidification transformation method. The method includes the steps that a layering injection pipe is deployed in a transformation oil stratum, the upper portion of the lower portion of the interlayer injection pipe are blocked, and the middle of the layering injection pipe is connected with a separated injection valve; transformation liquid is injected into the layering injection pipe, the transformation liquid comprises, by weight, 4-6 wt% of hydrochloric acid, 20-30 wt% of hydrofluoric acid, and the balance water, and the hydrochloric acid, the hydrofluoric acid and the water are used for finishing acidification transformation on an SAGD low-physical property interlayer; according to m rock stratum=rhoV=rho pi R2h/5, the quality of the transformation oil stratum is obtained, the rho is the rock stratum density, and the unit is g/cm<3>; the R is the processing radius, and the unit is m; the h is the thickness of the transformation oil stratum, and the unit is m; the amount of substance of the transformation oil stratum is solved; the consumption amount of HF is solved; finally, the consumption amount of HC1 and water is determined in combination with the HF consumption amount. The SAGD low-physical property interlayer acidification transformation method is reasonable and efficient, low in construction risk and high in success rate.