The present invention discloses a method and device for self-calibrating an antenna in a 
base station of a CoMP-based TDD 
system, where firstly the relative reciprocity {tilde over (w)}i of each pair of 
base station transmitter and 
receiver of the present 
base station relative to a calibration 
transmitter and 
receiver is calculated, and the relative reciprocity wi of each pair of base 
station transmitter and 
receiver of the present base 
station relative to a reference base 
station transmitter and receiver is calculated by selecting one pair of base station transmitter and receiver as the reference base station transmitter and receiver, wherein i=1, 2, . . . , N; then a measurement 
signal is transmitted from the calibration transmitter of the present base station to the calibration receiver, and a channel response hc,k of the calibration transmitter and receiver of the present base station is measured, wherein hc,k=hct,khcr,k, and k=1, 2, . . . , M; then a channel response hcr,k of the calibration receiver of the present base station is measured; next the absolute reciprocity wc,k of the calibration transmitter and receiver of the present base station is calculated in the formula ofwc,k=hc,k(hcr,k)2;and finally a global relative calibration weight ŵi of each pair of base station transmitter and receiver of the present base station from an acquired global reference wm is calculated in the formula ofw^i=w_iwtwm.The technical solution of the invention can perform 
antenna calibration of a CoMP-based TDD radio communication 
system.