The invention relates to an antioxidant skin-care composition containing ocean collagen degradation product and its application. The antioxidant skin-care composition is prepared from, by weight percent, 0.1-1.0% of tuna collagen hydrolysate, 0.05-0.5% of grape seed extract, 5.0-10.0% of glycerol, 5.0-9.0% of octadecanol, 1.0-5.0% of white oil, 1.0-5.0% of ethylhexyl palmitate, 3.0-5.0% of polydimethylsiloxane, 0.1-1.0% of glycerin monostearate, 0.3-0.9% of fatty alcohol-polyoxyethylene ether, 0.1-1.0% of dodecanol sodium sulfate, proper amount of antibacterial agent and essence, and the rest of low deuterium oxide. The tuna collagen hydrolysate and the grape seed extract are used as the main active components of the skin care product and play the effects of cooperating to resist oxidization, eliminating free radicals, and supplementing moisture loss, and others; low deuterium oxide is used as solvent, the zero oxidization of solvent can be reached, thus the skin care product can delay aging, moisten and replenish water.