135 results about "Collagen hydrolysates" patented technology

Compositions useful for treating inflammatory diseases including arthritis are disclosed which comprise cetyl myristoleate compounds or related compounds and at least one compound useful for treatment of inflammatory disease, such as tetracycline compounds, Cox-2 inhibitors, non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, local anaesthetics, chelating agents, matrix metalloprotease inhibitors, inhibitors of inflammatory cytokines, glucosamine, chondroitin sulfate and collagen hydrolysate. Also disclosed are pharmaceutical compositions and methods of treatment for inflammatory disease and local inflammation and dermal irritation. Also disclosed are compositions including tetracycline and at least one compound useful for treatment of inflammatory disease.

Compositions useful for treating inflammatory diseases including arthritis are disclosed which comprise cetyl myristoleate compounds or related compounds and at least one compound useful for treatment of inflammatory disease, such as tetracycline compounds, Cox-2 inhibitors, non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, local anaesthetics, chelating agents, matrix metalloprotease inhibitors, inhibitors of inflammatory cytokines, glucosamine, chondroitin sulfate and collagen hydrolysate. Also disclosed are pharmaceutical compositions and methods of treatment for inflammatory disease and local inflammation and dermal irritation. Also disclosed are compositions including tetracycline and at least one compound useful for treatment of inflammatory disease.

The invention relates to a Chinese medicine preparation, particularly a Chinese medicine preparation capable of increasing bone density and improving osteoporosis and arthralgia. The Chinese medicine preparation contains epimedium extract, radix salviae miltiorrhizae extract, D-glucosamine hydrochloride, biological calcium carbonate (oyster calcium), collagen hydrolysate, chondroitin sulfate and other active ingredients, wherein the D-glucosamine hydrochloride can obviously promote the proliferation and differentiation actions of the epimedium extract and radix salviae miltiorrhizae extract on osteoblasts. By combining the traditional Chinese medicine theory and the modern medicine research, the preparation tonifies the liver and kidney, strengthens the kidney and bone, promotes the bloodcirculation, dredges the collaterals and directly supplements calcium and collagen in a biological way, so that the kidney-qi is sufficient, and the bone is tonified, thereby improving ostealgia and arthralgia, enhancing the quality of life in the turn of life, and further performing the functions of increasing bone density and improving osteoporosis and arthralgia.

The invention provides a natural dyestuff dyeing method for a cellulosic fiber fabric. The method comprises the steps: inorganic tanning leftover is chosen to perform alkali hydrolysis to prepare collagen hydrolysate which is applied to finishing cellulosic fiber fabric, then the finished fabric is dyed through natural dyestuff, and a residual inorganic metal salt tanning agent in the collagen hydrolysate has a mordant effect in a natural dyestuff dyeing process; a diisocyanate cross-linking agent improves binding strength of collagen and the cellulosic fiber fabric. Compared with an unfinished cellulosic fiber fabric, nautral dyestuff dyeing performance of the cellulosic fiber fabric which is finished by collagen hydrolysate is obviously improved.

The invention relates to a bluefin tuna collagen hydrolyzate and a preparation method thereof. The method comprises the following steps: cleaning bluefin tuna bones, and immersing in an acidic solution to remove inorganic calcium salts; immersing in a sodium chloride solution to remove non-collagen impurity proteins; carrying out degreasing, fishy smell removal and enzymolysis on the treated fish bones, inactivating the enzyme at high temperature, and carrying out hydrothermal extraction to obtain a bluefin tuna collagen hydrolyzate solution; and drying to obtain the collagen hydrolyzate powder. The preparation technique is scientific and reasonable, and fully utilizes the unemployed fish bones in aquatic product processing as the raw material to develop the collagen hydrolyzate with potential market value; the composite enzyme degreasing, fishy smell removal and enzymolysis process is adopted while regulating the enzymolysis conditions of the composite enzyme, thereby greatly shortening the extraction time of the collagen hydrolyzate, preparing the tuna collagen hydrolyzate with different molecular weights and with the advantages of high gel strength, high oxidation resistance activity, high safety, no toxic or side effect and the like, enhancing the production efficiency and lowering the energy consumption.

The present invention is crosslinked chitosan-quaternized hydrolyzed collagen preparing process and relates to antibiotic biological material preparation. The crosslinked chitosan-quaternized hydrolyzed collagen is prepared with silkworm pupa chitin and hydrolyzed collagen as material. The preparation process includes mixing two kinds of solution, adding crosslinking agent to perform crosslinking reaction, membrane concentration, regulating pH value, and volumetric or spray drying to produce powder. The present invention can prepare solution or sol product and into the product, various water soluble functional factors, such as skin growth factor, moisture maintaining factor, vitamin, etc. may be added to form multifunctional biological dressing.

The invention discloses a cosmetic composition containing gold collagen. The cosmetic composition consists of nano-gold particles, collagen hydrolysate, phospholipids, 1,3-butanediol, hexanediol, pentanediol, ethylhexyl glycerin and a skin conditioning component. On one hand, nano-gold plays roles of activating superoxide dismutase, eliminating hydroxyl free radicals, promoting the proliferation of human epidermal cells and resisting decrepitude; on the other hand, the nano-gold particles, collagen hydrolysate and phospholipids are uniformly dispersed according to a microjet technology, interact and are combined through a charge or other ways; the nano-gold particles and the phospholipids have excellent affinity on skin cells and interact to promote the percutaneous absorption of small-molecule collagen hydrolysate, replenish collagen as well as related polypeptides and amino acids, promote skin repairing and collagen synthesis, so as to achieve skin repair effects of delaying skin aging and improving skin health.

The invention discloses a synthetic utilizing method of leather waste, which is characterized by the following: utilizing each component with collagen, chromate salt and retanned agent in the waste leather completely; improving the combining and filling effect of collagen hydrolysate in the retanned procedure greatly through modifying and coordinating with other retanned agent; simplifying the operation and method without secondary pollution.

The invention relates to a technique for preparing squid skin collagen peptide through an enzymic method. The technique includes: pre-treating squid skin which is a raw material, hydrolyzing through alkaline protease, and continuing hydrolysis through composite protease to obtain collagen hydrolysate, wherein the composite protease is composed of papain and flavorzyme. The collagen peptide prepared by the technique is ideal in hydrolysis degree, DPPH removal rate and polypeptide conversion rate, molecular weight of 97.63% of collagen peptide is less than 2000 Da, and the collagen peptide is high in quality and utilization value. The technique has high theoretical guiding significance in subsequent further separation and purification and application of the squid skin collagen peptide.

The invention discloses elastic protein peptide powder. The key points of the technical scheme are characterized in that the elastic protein peptide powder is prepared from the following components inparts by weight: 2,300-2,700 parts of fish collagen hydrolysate, 600-800 parts of blueberry juice powder, 600-800 parts of grape powder, 230-270 parts of cranberry juice powder, 50-350 parts of xylitol, 90-130 parts of green plum powder, 80-120 parts of acerola cherry fruit powder, 40-80 parts of type II collagen peptide hydrolysate, 80-120 parts of L-calcium lactate, 30-70 parts of soybean peptide, 8-14 parts of skipjack elastic protein peptide, 2-5 parts of blood orange powder, 10-14 parts of cubilose peptide, 80-120 parts of beet juice powder, 60-80 parts of citric acid and 1-5 parts of sucralose. The invention aims at providing the elastic protein peptide powder which can remarkably improve skin ageing.

The invention discloses a purple sweet potato anthocyanin drink. The drink is prepared from, by weight, 10 parts of purple sweet potato anthocyanin dispersoid, 40-60 parts of a fresh flower extracting solution, 20-30 parts of a fresh fruit extracting solution, 0.05-0.07 part of carboxymethylcellulose and 0.01-0.03 part of D-sodium erythorbate. According to the purple sweet potato anthocyanin drink, edible collagen hydrolysate is adopted as a carrier material, purple sweet potato anthocyanin is prepared into the purple sweet potato anthocyanin dispersoid, decomposition of effective constituents in the purple sweet potato anthocyanin occurring in the processing process is reduced to the greatest extent, no harmful residual solvent exists, the bioavailability of the purple sweet potato anthocyanin is remarkably improved, the synergistic effect is achieved when the purple sweet potato anthocyanin is combined with the fresh flower extracting solution and the fresh fruit extracting solution, and the drink is reasonable in formula, capable of being stored for a long time, extremely good in taste, capable of maintaining beauty and resisting to aging and suitable for being drunk for a long time.

The invention provides a production method for synthesizing an aqueous adhesive by using collagen modified by polyurethane and epoxy resin. The method includes: firstly, extracting a collagen hydrolysate from raw materials, such as leftover material of leather manufacturing, bones and the like, which contain the collagen, number-average molecular weight being 10,000 to 30,000; then at 50-80 DEG C,synthesizing an isocyanate-terminated polyurethane prepolymer containing a hydrophilic group and mixing the prepolymer with a certain amount of epoxy resin, and adding a salt-forming agent so as to form salts with carboxylic group; finally, adding deionized water, so that during dispersion and emulsion, the collagen hydrolysate can be subjected to grafting reaction with the polyurethane and epoxyresin, thereby synthesizing the aqueous adhesive based on the collagen modified by polyurethane and epoxy resin. In application, a curing agent and filler are not added, or are added to a certain amount, for adhesion of plywoods. With the leftover material of leather manufacturing being a main production raw material, which is reproducible, the product is free of formaldehyde, has excellent waterresistance and adhesion strength, is low in production cost, and can satisfy the use requirement of II-type plywoods. The production method is simple and is easy to control.

The present inventors have found that collagen hydrolysate can be favorably used for the preparation of an edible composition for limiting voluntary food intake and hence are suitable for prevention and treatment of overweight and obesity.

The invention discloses a method for rapidly preparing nano-silver particles. A collagen hydrolysate is adopted as an assistant; ascorbic acid is adopted as a reductant; silver nitrate is adopted as a raw material; and at a condition of room temperature, the nano-silver particles are synthesized rapidly. The nano-silver particles prepared with the method disclosed by the invention are uniform in grain size; the grain size is below 100 nm; and the nano-silver particles are good in dispersibility. The prepared nano-silver particles are applied to manufacture of a hydrogen peroxide non-enzyme sensor. As is shown by research, the hydrogen peroxide non-enzyme sensor can rapidly and accurately detect hydrogen peroxide; and the stability is high. The method disclosed by the invention is simple; the material is easily available; and the method is environment-friendly and convenient to promote.

The present invention relates to a food supplement composition for reducing fatigue, and / or improving recovery and resistance to fatigue. The composition comprised of collagen hydrolysate, blueberry extract and liquorice extract.

The invention relates to an antioxidant skin-care composition containing ocean collagen degradation product and its application. The antioxidant skin-care composition is prepared from, by weight percent, 0.1-1.0% of tuna collagen hydrolysate, 0.05-0.5% of grape seed extract, 5.0-10.0% of glycerol, 5.0-9.0% of octadecanol, 1.0-5.0% of white oil, 1.0-5.0% of ethylhexyl palmitate, 3.0-5.0% of polydimethylsiloxane, 0.1-1.0% of glycerin monostearate, 0.3-0.9% of fatty alcohol-polyoxyethylene ether, 0.1-1.0% of dodecanol sodium sulfate, proper amount of antibacterial agent and essence, and the rest of low deuterium oxide. The tuna collagen hydrolysate and the grape seed extract are used as the main active components of the skin care product and play the effects of cooperating to resist oxidization, eliminating free radicals, and supplementing moisture loss, and others; low deuterium oxide is used as solvent, the zero oxidization of solvent can be reached, thus the skin care product can delay aging, moisten and replenish water.

The invention discloses an anionic dye fixing agent with formaldehyde removal function and a preparation method thereof. The preparation method comprises the following steps: with N,N-methylene bisacrylamide and diethylenetriamine as raw materials and water as a solvent, preparing an amino-terminated hyperbranched polymer; carrying out graft copolymerization on collagen hydrolysate liquor and a monomer to prepare a cationic collagen copolymer; and finally, compounding the prepared amino-terminated hyperbranched polymer with the cationic collagen copolymer according to a mass ratio of 1:10 to 10:1 to obtain the anionic dye fixing agent with the formaldehyde removal function. Through the compounding of the amino-terminated hyperbranched polymer and the cationic collagen copolymer, the anionic dye fixing agent with the formaldehyde removal function is prepared; when the anionic dye fixing agent with the formaldehyde removal function is used in the dyeing process, the dye-uptake and color fastness of leather can be effectively increased, and the content of formaldehyde in the leather can be decreased.

The use of collagen hydrolysate as dietary supplement to baby food, particularly to improve the general state of health in infants and bring about a reduction in restlessness, vomiting after food intake and flatulence, is disclosed.

The invention discloses a method for preparing a plurality of metal ion leather tanning agents by utilizing chromium-containing and collagen solid wastes. Materials belonging to leather originally such as leather meal, leather bits and pieces, waste leather are used as raw materials for preparing chemical material which can be processed into leather; the chemical material is used in leather tanning and then is applied back to the leather; the chemical material has the best compatibility with the leather and can effectively form the self-closed recycle of materials. Namely, the chromium-containing and collagen solid wastes are used as a reducing agent instead of glucose, sulfur dioxide, etc., and ferrous sulfate is used as a supplementary reducing agent, so as to deoxidize sodium bichromate to prepare the leather tanning agents; chromium compounds in the solid wastes again become part of the metal ions which are used for preparing the tanning agents; collagen hydrolysate or oxidation products become filling materials in the tanning agents; the supplementary reducing agent becomes another metal ion in the tanning agents after being oxidized; the leather tanning agents containing a plurality of metal ions are prepared through the bridge link between sodium citrate and sodium tartrate.

The invention relates to a preparation method for antioxidant meat paste. The method comprises the following steps: firstly, by taking fresh or frozen soft-shelled turtle skirt edge as a raw material, extracting collagen under the conditions of ultrasonic frequency of 20-24kHz and ultrasonic powder of 50-100W; adding 0.8-1.6% of alkaline protease for performing enzymolysis treatment on the collagen, thereby obtaining collagen zymolyte; performing dialysis and separation and then freeze-drying; and adding 0.25-1% of collagen zymolyte into the meat paste, thereby obtaining the antioxidant meat paste. The preparation method provided by the invention is simple; the steps are easily operated; the antioxidant activity of the collagen zymolyte acquired according to an ultrasonic assisting zymolytic method is excellent; the antioxidant activity is increased along with the increasing of the concentration of the collagen hydrolysate; after a certain amount of collagen zymolyte is added into the meat paste, the peroxidation of the protein and fat in the meat product can be restrained; and the shelf life of the meat paste can be prolonged.

The invention provides cosmetic composition with a balanced whitening effect. The cosmetic composition comprises the following raw materials: pongamia glabra seed oil, pearl powder, collagen hydrolysate, barley seed extract, Brassica juncea var. crispifolia extract, zizania latifolia extract, cherry extract, magnesium ascorbyl phosphate, glycerin and hyaluronic acid. Compared with the prior art, the cosmetic composition has the following beneficial effects: the cosmetic composition has the effects of removing skin garbage, cooling and activating blood, dredging pores, supplementing nutrition and moisturizing the skin to achieve freckle removal and whitening, has no toxic or side effects, is applicable to oily skin and people with acne, cyasma, chloasma and butterfly rash and has certain curative effect on freckles.

Toilet paper is made from 80-300 parts of paper pulp, 12-19 parts of ethyl acetate, 16-36 parts of magnesium stearate, 3-9 parts of ethylene, 4-9 parts of hydrogenated oil, 4-11 parts of pigment, 12-21 parts of choline, 1-4 parts of lactic acid, 6-9 parts of castor oil, 10-20 parts of peanut oil, 3-8 parts of chondroitin sulfate, 16-18 parts of collagen hydrolysate, 1-3 parts of pearl powder, 23-31 parts of glycerin, 1-4 parts of theophylline, 3-8 parts of yeast and 3-8 parts of glycol. The toilet paper does not contain a fluorescent agent and is beneficial to health.

The present invention relates to a composition in the form of compacted particles, comprising at least 5 wt %, preferably at least 10 wt %, more preferably at least 15 wt %, of gelatin and / or collagen hydrolysate.

The present invention relates to a method for extracting collagen using ultrasonic wave generator. More particularly, the present invention relates to a method for extracting collagen, comprising: a first step of treating fish skin with ultrasonic waves in the presence of an acid solution to obtain collagen extracts; a second step of separating collagen and the ultrasonically treated fish skin from the collagen extracts; and a step of repeating the first and second steps for the ultrasonically treated fish skin to further extract collagen. In addition, a collagen separation apparatus using ultrasonic waves according to the present invention comprises: a sample tank in which fish skin is accommodated; a separation unit which receives fish skin from the sample tank, separates collagen from the fish skin, and supplies the separated collagen back to the sample tank; and a unit for generating ultrasonic waves, which is connected to the separation unit to generate ultrasonic waves in order to separate collagen from the fish skin. The method for extracting collagen according to the present invention may enable collagen to be extracted using an acid solution having a lower concentration than those used in existing methods, may enable collagen to be extracted at a high yield rate, and may enable collagen having a high molecular weight to be extracted while maintaining the basic structure of the collagen, and not in the form of collagen hydrolysate.

The invention relates to a product for rejuvenating and beautifying and a preparation method thereof. The preparation method comprises the following steps: adding bletilla striata polysaccharide into distilled water which is 4-25 times of the weight of the bletilla striata polysaccharide and has a temperature of 50-70 DEG C; adding collagen hydrolysate having a molecular weight of lower than 3000, uniformly stirring, and insulating for 10-60 minutes; adding dihydromyricetin, pearl powder and bletilla striata gel, and immediately deoxidizing by adopting ultrasonic wave treatment to accelerate dissolution; drying in vacuum to reduce the moisture content to be lower than 30 percent after 3-30 minutes of ultrasonic wave treatment; and storing by adopting vacuum package for later use. According to the method, the solubility of dihydromyricetin can be remarkably improved by sufficiently utilizing the collagen hydrolysate and bletilla striata saccharides, and the stability of the dihydromyricetin can be facilitated since the pH value of the dihydromyricetin solution is partially acidic.

The aim of the invention is to obtain a food product, in particular a snack product, which has a favourable nutrient physiology and a crispy, brittle texture, and an associated production method. To achieve this, the food product is substantially devoid of starch and has a foamed structure and the solid content has a protein fraction of at least approximately 25% by weight, at least 65% by weight of the protein fraction consisting of gelatin and / or collagen hydrolysate.

The invention discloses a hair conditioner. The hair conditioner comprises the following substances in parts by weight: 1-3 parts of octadecyl dimethyl benzyl ammonium chloride, 1-2 parts of cetyl alcohol, 1-3 parts of cetyltrimethyl ammonium chloride, 1-2 parts of octadecyl dimethyl tertiary amine, 3-5 parts of myristic acid, 0.5-1 part of citric acid, 0.2-0.6 part of collagen hydrolysate, 2-4 parts of hydroxyethyl cellulose, 1-3 parts of propylene glycol, 0.5-1 part of fragrance, 0.1-0.3 part of methyl paraben and 300-400 parts of distilled water.

The invention provides recycled paper and a preparation method thereof. The recycled paper comprises waste paper, choline, collagen hydrolysate, pearl powder, chondroitin sulfate powder, theophylline and plant pigment essence. The preparation method includes the steps of paper smashing, pulp washing, color preparing, pulp dredging, drying and forming. The recycled paper has the advantages of repeatedly using waste paper, being environmentally friendly, sanitary, safe and reliable, saving tree resources, protecting ecological environment, and being simple in production technological process and convenient to operate.

The present invention relates to the use of compositions comprising hyaluronic acid and dermatan sulphate for the preparation of medicaments to be orally administered for the treatment of osteoarthritis and osteoarthritis-associated articular pain. The present invention also relates to the use of compositions comprising hyaluronic acid and dermatan sulphate for the preparation of a food or a food supplement to nourish the synovial fluid in a joint, and to improve articular mobility. The compositions may also contain collagen hydrolysate and nucleic acids.