The invention provides a noise reduction processing method and device, equipment, a storage medium and a program, and the method comprises the steps: obtaining a first noise signal (namely, a broadband noise signal) in an auricle external environment collected by a first microphone, and carrying out the filtering processing of the first noise signal through a feed-forward filter, and generating a second noise signal (namely a narrow-band noise signal) corresponding to the external environment of the auricle, filtering the second noise signal through a notch filter to obtain a second filtered signal, and further performing noise reduction processing on the noise reduction earphone according to the first filtered signal and the second filtered signal. Through the above process, the noise reduction earphone not only can eliminate broadband noise in the external environment of the auricle, but also can eliminate narrowband noise in the external environment of the auricle, so that the noise reduction effect can be ensured even in a scene with complex environmental noise.