The invention discloses an aluminum alloy section for physical laboratory cabinet and a preparation method thereof. An alloy comprises, by weight, 4.2 to 5.4% of Zn, 1.8 to 2.6% of Mg, 0.15 to 0.35% of Cu, 0.3 to 0.7% of Mn, 0.05 to 0.25% of Cr, no more than 0.15% of Ti, 0.3 to 0.6% of Si, no more than 0.25% of Fe, 0.1 to 0.2% of Zr, 0.08 to 0.14% of Cd, 0.04 to 0.06% of In, 0.3 to 0.05% of Sc, 0.025 to 0.045% of Er and 0.01 to 0.02% of Tm, with the balance being Al. According to the invention, through optimization of alloy components and reasonable arrangement of heat treatment technology, the prepared aluminum alloy section has excellent comprehensive mechanical properties, tensile strength of no less than 450 MPa and non-proportional extension strength of no less than 400 MPa, can substantially improve safety performance of the aluminum alloy laboratory cabinet, is applicable to preparation of the physical laboratory cabinet without dependence on import materials and has important economic benefits.