The invention discloses a thick-film magnetic isolation direct current solid-state power controller which comprises a power MOSFET (metal oxide semiconductor field effect transistor), a detection resistor, a power diode, a TVS (transient voltage suppressor) diode, a current conditioning circuit, a voltage detection circuit, a voltage state judgment circuit, a current state judgment circuit, an immediate trip circuit, an inverse time circuit, a short-circuit detection circuit, a driving circuit, a state synthetic circuit, a trip state latch circuit, a time delay reset circuit, a time sequence matching circuit, a DC/DC (direct current/direct current) isolated power supply, a first isolation circuit, a second isolation circuit, a third isolation circuit, a state feedback interface circuit, a control signal interface circuit and a power-on reset circuit. The circuit structure can optimize the electrical properties of the controller, reduce the volume and the weight, improve the reliability and is widely applied to civil low-voltage direct current power distribution systems, aviation, aerospace, tanks, automobiles, ships and other fields.