32 results about "Sleep Apnea Hypopnea Syndrome" patented technology

Disclosed is a sleep breathing pathological typing method, comprising: obtaining the frequency of respiratory disorder events in a snoring interval during the sleep of a monitored person, wherein the snoring interval is a period from the end of a snore to the start of the next snore (S101, S201); and performing typing according to the frequency of respiratory disorder events in the snoring interval, wherein the respiratory disorder events comprise hypopnea and apnoea (S102, S202, S203, S204). The method performs the typing of snoring according to the frequency of respiratory disorder events in the snoring interval, closely connects snoring with breathing disorder events, makes the analysis of snoring more detailed and specific, enriches the research in the field of snoring, and lies the foundation for the diagnosis of sleep apnea hypopnea syndrom via snoring analysis.

The invention discloses a modeling device for a mouse with an OSAHS (obstructive sleep apnea hypopnea syndrome). The modeling device comprises a mouse body container, a head cylinder, an opening and closing mechanism and an air bag, wherein the mouse body container is used for accommodating a mouse body; the head cylinder is used for accommodating the mouse head, and the mouse body container is communicated with the head cylinder; the air bag is located in a position where the mouse body container and the head cylinder are communicated, a through hole allowing penetration of the mouse head is formed in the air bag, and the air bag can locate the mouse neck and block air ventilation between the mouse body container and the head cylinder during inflation; an air hole is formed in one end of the head cylinder, and the opening and closing mechanism is matched with the air hole and used for controlling opening and closing of the air hole. The device can comprehensively stimulate a pathophysiological process of the OSAHS, thereby providing a good animal model for basic research of the OSAHS.

The invention discloses a household preliminary detecting system of SAHS (Sleep Apnea Hypopnea Syndrome). The household preliminary detecting system comprises a collecting device and an intelligent detecting device, wherein the collecting device is used for collecting snoring audio data of a patient; the intelligent detecting device is used for receiving the snoring audio data and carrying out preliminary detection; the collecting device is connected with the intelligent detecting device; and the intelligent detecting device comprises a collecting module which is used for collecting snoring data, a detecting module which is used for calculating an AHI (Apnea Hypopnea Index) value, and a judging module which is used for presetting a threshold value, and the patient can be determined to suffer from suspected SAHS if a current AHI value is larger than the threshold value.

The invention relates to an elastic tongue dorsum traction apparatus and a method for implanting the same. The elastic tongue dorsum traction apparatus and the method are used for treating patients suffering from sleep apnea-hypopnea syndromes or snoring. The elastic tongue dorsum traction apparatus comprises a tongue dorsum connecting mechanism, elastic traction bodies and tooth-side fixators. A support body of the tongue dorsum connecting mechanism is implanted under the mucosa of the tongue dorsum of a patient, and the elastic traction bodies and the tongue dorsum connecting mechanism are exposed out of the mucosa of the tongue dorsum of the patient. The tooth-side fixators are fixed to the inner sides of the teeth or the alveolar bones of the patient, one end of each elastic traction body is connected with the corresponding tooth-side fixator, and the other end of each elastic traction body is connected with the tongue dorsum connecting mechanism. The elastic tongue dorsum traction apparatus and the method have the advantages that the tooth-side fixators are used as support points, the elastic traction bodies can exert elastic tractive force on the tongue dorsum connecting mechanism, accordingly, the glossocoma tongue of the patient can be pulled up forwardly, airway stenosis and obstruction of the glossopharyngeal part of the patient can be prevented, and snoring and OSAHS (obstructive sleep apnea-hypopnea syndrome) treatment effects can be realized; an elastic traction effect is realized for the tongue dorsum connecting mechanism by the elastic traction bodies, so that movement of the tongue of the patient is unaffected while the tongue of the patient is moderately pulled up, certain swallowing and speaking functions can be kept, the airway of the glossopharyngeal part of the patient can be expanded, and the patient feels comfortable when using the elastic tongue dorsum traction apparatus.

The invention relates to an obstructive sleep apnea-hypopnea syndrome (OSAHS) screening method and a device. Formant characteristics of snore are adopted as technical indexes for screening OSAHS; Snore sections are extracted by a short-time energy method at first, then LPC (linear predictive coding) is used for modeling, after predicting factors of the LPC are obtained, a first formant frequency of each snore section is obtained by a root extraction method, as ranges of formant frequencies of different modes are different, the different snore sections can be distinguished, all first formant frequencies of all snorers are classified, by the aid of K mean values, and thresholds for distinguishing normal snore and abnormal snore of individuals are determined according to classified results; and then AHI (apnea-hypopnea indexes) in a PSG (polysomnogram) are simulated so that average times of apnea and hypopnea of the snorers within an hour are obtained. According to the OSAHS judgment standard, whether the data section has snore of a normal person or snore of a patient with the OSAHS is judged. The obstruction sleep apnea-hypopnea syndrome screening method and the device are low in cost, high in applicability and simple in operation and are non-contacting.

The invention discloses a salvia miltiorrhiza extract, an injection and an application thereof, and relates to the technical field of medicinal chemistry. The preparation method of the salvia miltiorrhiza extract specifically comprises: activating the strains, inoculating Beauveria bassiana on SDA medium for cultivation; amplifying the strains, inoculating the above-mentioned activated strains in a liquid medium and culturing them to obtain the strains culture medium; the medicinal material is fermented, the salvia miltiorrhiza is crushed into powder, water is added, sterilized, and the bacterial culture liquid containing cryptochlorogenic acid is added for fermentation to obtain the fermented medicinal material; the fermented medicinal material is obtained by separating and purifying, soaking the above-mentioned fermented medicinal material with methanol aqueous solution, ultrasonication, filtration, reduction The extract of Danshen was obtained by rotary steaming. The prepared salvia miltiorrhiza extract has high yield, excellent pharmacological activity and enhanced anti-inflammation effect; it can be made into injections for treating obstructive sleep apnea hypoventilation syndrome combined with hypertension, and the effect is remarkable.

The invention provides a method for evaluating a respiratory airflow stimulating factor during reopening of an air passage. The method can be applied to electrostimulation and respirator triggering methods for treating SAHS (Sleep Apnea Hypopnea Syndrome) patients and can also be applied to some sleep intervention methods for treating SAHS, for example adjustment on trigger points of sleep postures with pillows. The method comprises the following steps: S1. separately acquiring a breast band signal Tho and an abdominal band signal Abd of a respiration event during the reopening of the air passage, so as to calculate a pulmonary volume change; S2. calculating a pulmonary negative pressure change by using the pulmonary volume change; evaluating negative-pressure factor stimulation by using the pulmonary negative pressure change; S3. acquiring a blood oxygen signal of the respiration event during the reopening of the air passage, and calculating a blood oxygen lowering maximum value and a maximum lowering speed, so as to evaluate chemical factor stimulation; S4. evaluating the size of the respiratory airflow stimulating factor required during the reopening of the air passage by using the negative-pressure factor stimulation and the chemical factor stimulation as joint stimulating factors.

The invention provides a traditional Chinese medicine composition, which, in parts by weight, comprises: 3-30 parts of traditional Chinese medicines for invigorating spleen and lung qi; 3-20 parts of Atractylodes Rhizoma; 3-40 parts of Poria; ; Angelica 3-30 copies; blood-activating traditional Chinese medicines 6-60 copies; licorice 3-60 copies; heat-clearing and detoxifying traditional Chinese medicines 9-130 copies. Compared with the prior art, the present invention uses traditional Chinese medicines of the spleen and lung type, Atractylodes Rhizoma, Poria, and the traditional Chinese medicines of nourishing kidney-yang as the monarch medicine, which can aim at the root of the deficiency of the viscera, strengthen the spleen and the kidney, and eliminate the source of phlegm. Qi can help promote blood circulation and go out with toxins, nourishing qi and nourishing yin to help sleep; Angelica, blood-activating traditional Chinese medicines, and heat-clearing and detoxifying traditional Chinese medicines are ministerial medicines, clearing heat and detoxifying, promoting blood circulation and removing blood stasis, dispersing viscera and supporting qi; Dispelling phlegm and relieving cough, and detoxification; the whole recipe has the effect of removing blood stasis and detoxification, strengthening the root and dredging collaterals, so that the congestion can be removed, the root deficiency can be solidified, and it is used in the treatment of chronic obstructive pulmonary disease and / or sleep apnea hypopnea syndrome. achieved better results.

The invention relates to the field of molecular biology and medicines, and discloses a variation site of an obstructive sleep apnea hypopnea syndrome susceptibility gene ADIPOQ and a detection method and application of the variation site in detecting susceptibility of obstructive sleep apnea hypopnea syndromes. The invention further discloses a method for predicting the risk of the obstructive sleep apnea hypopnea syndromes by detecting the genotype of the variation site. The method comprises the following steps: extracting genomic DNA (Deoxyribonucleic Acid) of a sample, performing specific amplification, performing detection, analyzing the genotype of the variation site, and the like. Tests show that if the site has genotype variation, the risk of the obstructive sleep apnea hypopnea syndromes is increased. The invention further discloses a kit for detecting the susceptibility of the obstructive sleep apnea hypopnea syndromes.

The invention discloses a detection system for the sleep apnea hypopnea syndrome. The detection system comprises a fingertip signal acquisition device, a signal conversion module and a data processing module, wherein the fingertip signal acquisition device acquires photoelectric signals, representing blood volume change, in a fingertip blood vessel, converts the photoelectric signals into photoplethysmography data, and wirelessly transmits the photoplethysmography data to the signal conversion module in real time; the signal conversion module receives the photoplethysmography data output by the fingertip signal acquisition device, acquires blood oxygen saturation data, heart rate variability data and pulse rate via filter processing and calculation, and transmits the acquired data to the data processing module; the data processing module outputs sleep state data and respiratory event data based on the photoplethysmography data and the like. The detection system is simple and easy to use, and high in accuracy; the problem that conducting wires are arranged complexly during multi-conduction detection is solved.