The invention discloses a universal interface system for a multifunctional radio-frequency module, and belongs to the technical field of communication. The universal interface system comprises a system control management module, a universal bus interface module and a universal radio-frequency module, wherein the system control management module communicates with the universal bus interface module through a synchronous bus, and is used for issuing a system message, a control command and data, and receiving and processing self-check and state information reported by the universal radio-frequency module through the universal bus interface module at the same time; the universal bus interface module is a bridge between the system control management module and the universal radio-frequency module, and is used for finishing forwarding and processing of a system control command and data forwarding; and the universal radio-frequency module is applied to receiving-transmitting and up / down conversion of radio-frequency signals and modulation and demodulation of baseband signals, and executing the control command issued by the system control management module. The universal interface system is applied to radio communication, navigation and monitoring systems. Through adoption of the universal interface system, the system integration testing amount can be reduced effectively, and the system stability is improved.