The invention discloses an uterine cavity medicine infusion device. According to the technical scheme, the uterine cavity medicine perfusion device is characterized by comprising a medicine supply mechanism and an inflation mechanism, the medicine supply mechanism is connected with a catheter, the catheter is connected with an insertion tube used for being inserted into a uterine cavity, the insertion tube comprises an insertion head and a tube body, an annular groove is formed in the front end of the tube body, and the front end of the tube body is detachably connected with the insertion head; and an annular groove is fixedly connected with an annular first air bag, the first air bag is connected with an inflation pipe, and the inflation mechanism is connected with the inflation pipe. Compared with the prior art, the infusion device has the advantages that when the infusion device is used, a medical worker inserts the insertion tube into the uterine cavity through the vagina, the inflation mechanism inflates the first air bag through the inflation tube so that the first air bag can be expanded, the uterine cavity is closed, the medicine supply mechanism enables liquid medicine to enter the uterine cavity through the catheter and the insertion tube, the medicine is not prone to flowing out of the uterine cavity, and therefore, the medicine is ensured to play a sufficient role and the curative effect is improved.