A 3D-HEVC inter-frame information hiding method based on visual perception includes steps of information embedding and information extraction. In the step of information embedding, the human visual perception characteristic is considered, stereo salient images are obtained by a stereo image salient model, and the stereo salient images are divided into salient blocks and non-salient blocks with an otsu threshold. The coding quantization parameters are modified according to different modulation rules for different regions. Then, based on the modified quantization parameters, the coding-tree-units are coded to complete the information embedding. In the step of information extraction, no original video is needed, no any side information needs to be transmitted, and the secret information can be blindly extracted. The present invention combines with the human visual perception characteristic, and selects P frames and B frames as embedded frames for effectively reducing the decrease of the stereo video subjective quality.