The invention discloses a large-scale numerical control machine tool fault monitoring system based on multi-sensor. The large-scale numerical control machine tool fault monitoring system based on themulti-sensor comprises a sensor module, a data acquisition module, a summary module, a data analysis module, an information monitoring module, a controller, a data interconnection module, a storage module, a data processing module, an emergency stop button, an alarm, a data calculation module and a warning light; after obtaining Ti and Yi, the data analysis module in the invention transmits the Tiand Yi to the information monitoring module; the information monitoring module compares Ti and Yi with preset values t and y separately, generates an overhauling signal and a replacement signal, andtransmits the overhauling signal and the replacement signal to the data interconnection module through the controller; and the data interconnection module displays the received overhauling signal andreplacement signal on the mobile phone of the staff, which is convenient for the staff to understand the wear condition of the tool over a period of time, and to overhaul and replace the tool with a large degree of wear.