The invention discloses a solubleand efficient recombinant expression methodfor fibroblast growth factor protein. In the method, as for an escherichia coli strain of a carrier containing coding-recombinant fibroblast growth factor family protein, expression of intracellularactive protein is promoted by adding a certain dosage of monosaccharide during induction.The fibroblast growth factor family protein comprises FGF1, FGF2, FGF4, FGF7, FGF8, FGF9, FGF11, FGF15, FGF18, FGF21, FGF23 and mutants of the fibroblast growth factor family protein. As for the process that the certain dosage of monosaccharide is added during induction, the monosaccharide is supplemented into before an inductive agent is added, or the monosaccharide is supplemented into while an inductive agent is added, or the monosaccharide is supplemented into after the inductive agent is added. The technology prejudice that expression of lac and araoperons is inhibited by glucose in escherichia colirecombinant is overcome inthe technical field, and the method capable of efficiently promoting expression of the fibroblast growth factor protein in escherichia coli is applied.