The invention discloses a multi-stage nine-grid locating method of spatial information. Firstly, figure orthophotoquad in the target area is made; basic grid partition for the target area is carried out, and then multi-stage nine-grid is drawn in an overlapped mode in the target area, and is respectively called the basic grid, the first-stage nine-grid, the second-stage nine-grid, the third-stage nine-grid and so forth; the nine-grid takes the basic grid as the initial grid, and multi-stage partition is carried out on the basic grid to form each-stage sub-grid; a multi-stage nine-grid code is composed of each-stage nine-grid code where sub-grids are positioned, and certain geographic element or event spatial location in the target area is determined by a grid code; at last, mutual conversion relationship of nine-grid code and space coordinate is established so as to realize multi-stage nine-grid locating of spatial information. The invention has simple code for representing geographic element or event spatial location, is in accordance with location judgment habit of people, ensures information collection to be more convenient and quicker, greatly improves work efficiency and saves cost.