The invention relates to an integrated multimodal
artificial intelligence platform designed to function as an autonomous
hospital system providing end-to-end
health prevention, screening, diagnosis, treatment optimization, and longitudinal digital-twin-based monitoring. The platform introduces a closed-loop clinical architecture that continuously analyzes heterogeneous
patient data including
radiology,
pathology,
genomics, laboratory findings, longitudinal clinical records, wearable streams, and environmental exposures. A multimodal
transformer (MT-X) generates a unified patient-specific representation, enabling high-precision diagnostic and prognostic
inference. A novel Autonomous Screening Interval Generator (ASIG) dynamically determines individualized screening schedules based on calibrated risk models and temporal
disease-evolution forecasting. A Digital Twin Engine (DTE) simulates
tumor progression,
metastasis probability,
toxicity trajectories, and
therapy response. An Adaptive Therapy Optimization Engine (ATOE), based on
reinforcement learning, identifies
optimal treatment strategies tailored to patient
biology and
system-level constraints. The invention is industrially applicable to hospitals, centers, national
screening programs, tele-networks, and Al-enabled health systems. The integrated nature of the invention, the closed-loop framework, and the combination of digital-twin
simulation with intelligent screening and therapy design constitute a substantial improvement beyond conventional medical Al solutions.