The invention relates to the technical field of POI 
big data processing, in particular to a 
population data spatialization method, device and equipment based on multi-source 
information fusion, and the method comprises the steps: obtaining night light data, urban POI data and 
population data of a research region, dividing a 
spatial distribution grid in the research region according to a preset rule, and building a 
population data spatialization model with sub-
population data as a dependent variable, wherein the sub night light data is a multivariate 
linear regression model of independent variables; according to a multivariate 
linear regression model taking the sub night light data as an independent variable, determining an initial estimated value of population distribution of each spatialdistribution grid according to the multivariate 
linear regression model, taking the sub 
population data of the administrative region as a constraint condition to correct the initial estimated value ofthe 
spatial distribution grid in the administrative region, and determining a population prediction value. According to the method, night light data and POI data are combined, a 
regression analysis model is constructed according to 
demographic data, demographic spatial modeling is carried out, demographic 
spatial distribution simulation and prediction are realized, the data has no 
hysteresis quality, and the model accuracy is relatively high.