The invention discloses an intelligent location tracking manipulation pen and a processing method of spatial interaction sensor original data. The manipulation pen comprises a pen-like shell and an intelligent control circuit board, the intelligent control circuit board is arranged in a containing cavity of the pen-like shell, and the intelligent control circuit board comprises a motion sensor, a processing unit, a communication unit, a feedback prompting unit and a space coordinate signal unit. The method comprises the steps that firstly, the motion sensor detects parameters of a manipulation pen sensor; secondly, the processing unit reads the original data of the manipulation pen sensor, and whether the original data of the sensor is valid or not is judged; thirdly, the processing unit conducts average filtering on the original data of the sensor, and the euler angle parameter and the quaternion of the manipulation pen are obtained; fourthly, the euler angle parameter and the quaternion of the manipulation pen are transmitted to a special interactive device through the communication unit, and a spacial sensor of the manipulation pen is determined. The drift phenomenon is solved, a nine-axis motion sensor and the infrared track technology are utilized, so that the precision for tracking the spacial sensor of the manipulation pen is greatly improved, and the user experience is improved.