Disclosed is a method of treating Psychotic Depression, Suicidal Ideation, Disruptive
Mood Dysregulation Disorder, Persistent Depressive Disorder (Dysthymia),
Premenstrual Dysphoric Disorder, Substance / Medication-Induced Depressive Disorder, Depressive Disorder Due to Another Medical Condition, Other Specified Depressive Disorder, Unspecified Depressive Disorder, Separation
Anxiety Disorder, Selective Mutism, Specific Phobia,
Social Anxiety Disorder (Social Phobia),
Panic Disorder,
Panic Attack (Specifier), Agoraphobia,
Generalized Anxiety Disorder, Substance / Medication-Induced
Anxiety Disorder,
Anxiety Disorder Due to Another Medical, Other Specified
Anxiety Disorder, Unspecified
Anxiety Disorder, or fatigue, the method including administering a pharmaceutical composition containing an effective amount of an
active agent, wherein the
active agent is purified (2R,6R)-hydroxynorketamine, purified (2S,6S)-hydroxynorketamine, or a combination thereof, or a pharmaceutically acceptable saltthereof, together with a pharmaceutically acceptable carrier to a patient in need of such treatment.