A pharmaceutical preparation for prophylaxis against and treatment of
Staphylococcus induced infections or conditions in humans and animals, is disclosed, wherein it comprises a combination of a) one or more viable α-
Streptococcus strains chosen from the group consisting of the
Streptococcus sanguis II strains having the accession numbers NCIMB 40104, NCIMB 40105, NCIMB 40106, and NCIMB 40873, the
Streptococcus mitis strains having the accession numbers NCIMB 40107, and NCIMB 40874, the Streptococcus oralis strains having the accession numbers NCIMB 40875 and NCIMB 40876, the
Streptococcus lactis strain L1A having the accession number NCIMB 40157, and one or more variants thereof having the same or essentially similar effect; and b) one or more viable
Lactobacillus strains chosen from the group consisting of the
Lactobacillus rhamnosus strain LB21 having the accession number NCIMB 40564, the
Lactobacillus plantarum strain LB3 having the accession number DSM 17852, and the
Lactobacillus plantarum strain LB7 having the accession number DSM 17853, and one or more variants thereof having the same or essentially similar effect; in at least one pharmaceutically acceptable medium in which said strains maintain their viability, as well as a kit for and a method of prophylaxis and treatment of
Staphylococcus induced infections and conditions, and use