The invention provides a vital sign monitoring system. The system comprises a sensing measurement assembly, a microprocessor communicating with the sensing measurement assembly and an intelligent terminal communicating with the microprocessor; the sensing measurement assembly is used for collecting vital sign information of a human body, converting the vital sign information into a vital sign electric signal and sending the vital sign electric signal to the microprocessor, wherein the vital sign information comprises a body temperature value, a heart rate value, the blood oxygenation content, electrocardiogram data and electroencephalogram data. The vital sign monitoring system can be used for continuously measuring vital signs such as the body temperature, the heart rate, blood oxygen, electrocardio, electroencephalogram and blood pressure simultaneously, use of the system is convenient, the vital sign information can be measured continuously on the basis of not affecting daily life of a user, according to the system, automatic diagnosis and recognition on abnormal signals of the user are achieved through signal collection and signal analysis and processing, the burdens of medical staff are greatly reduced, carrying and use are convenient, and normal life of the user is not affected.