The invention relates to a regulating valve, in particular to a high-pressure and micro-flow tandem type regulating valve, and belongs to the technical field of control valves. The high-pressure and micro-flow tandem type regulating valve comprises a valve body, wherein a valve seat is arranged in the valve body, a second gasket is arranged between the valve body and the valve seat, a guide pressing sleeve is arranged at the upper end of the valve seat, the upper end of the valve body is connected with an upper cover through a bolt, the upper cover tightly presses the guide pressing sleeve and the valve seat in the valve body, and a first gasket is arranged between the valve body and the upper cover. The upper end of the upper cover is connected with a packing pressing board through a bolt. A valve element assembly is installed in the valve seat in a matched mode, the upper end of the valve element assembly penetrates through the guide pressing sleeve, the upper cover extends out of the packing pressing board, packing is arranged between the valve element assembly and the upper cover, a packing pressing cover is arranged between the packing and the packing pressing board, and the packing pressing board tightly presses the packing pressing cover and the packing. According to the high-pressure and micro-flow tandem type regulating valve, the tandem type structure is adopted, the multi-stage depressurization function is achieved, the flow velocity of media is reduced, the inner parts of the valve are protected effectively, and the noise of the valve is lowered; meanwhile, the phenomenon that as the throttling area is small when micro-flow regulation is performed, the valve is blocked can be avoided; the valve element assembly is of a double-guide structure and is prevented from bending and deforming, the regulation stability of the valve is improved, and the service life of the valve is prolonged.