The invention relates to fructus caricae papayae 
wine, a preparation method of the fructus caricae papayae 
wine, and applications of the fructus caricae papayae 
wine. According to the fructus caricaepapayae wine, fructus caricae papayae is scientifically fermented, thus fructus caricae papayae raw wine is prepared, the fructus caricae papayae raw wine is blended with 
white wine, fructus caricae papayae is adopted as the monarch 
drug, radix puerariae, loquat honey and radix glycyrrhizae are adopted as the raw materials, 
high fructose corn syrup and white granulated 
sugar are adopted as blending agents, and an appropriate amount of auxiliary material is also adopted. The preparation method comprises the following steps: (1) taking fresh fructus caricae papayae, washing the fructus caricae papayae to be clean, carrying out dicing and deseeding, carrying out breaking treatment, and carrying out enzymolysis; (2) adjusting the ingredients, carrying out 
fermentation, carrying out fining clarifying, and carrying out 
ageing to obtain the fructus caricae papayae raw wine; and (3) adding radix puerariae, loquat honey and radix glycyrrhizae, carrying out blending and membrane 
filtration, carrying out filling, and carrying out opening sealing, thus obtaining the fructus caricae papayae wine. The prepared fructus caricae papayae wine is high in 
clarity, the content of volatile acid is low,the content of fusel oil is low, the wine quality is mellow and smooth, sweet 
aftertaste is obtained, the 
flavor and 
mouthfeel are excellent, and the fructus caricae papayae wine has the anti-tumor 
efficacy, and is especially suitable for high-end white-collar women. The fructus caricae papayae wine also can be widely applied to preparation of various health wines and drinks, and has the wide market prospect.