69 results about "Hepatitis X" patented technology

The present invention relates to therapeutic combinations comprising (a) Compound (1), or a pharmaceutically acceptable salt thereof, as herein described, (b) an interferon alfa and (c) ribavirin. Compound (1) is a selective and potent inhibitor of the HCV NS3 serine protease. The present invention also relates to methods of using such therapeutic combinations for treating HCV infection or alleviating one or more symptoms thereof in a patient.

The invention provides novel application of 4-hydroxy salicylamide in the field of pharmacy. The compound is an inhibitor of ribonucleotide reductase (RR), and can achieve the aims of inhibiting replication of HBV and treating hepatitis, in particular the hepatitis B by inhibiting activity of RR enzyme to block synthesis of dNTPs (deoxynucleotide triphosphates) required by hepatitis B virus (HBV)replication, achieve the aim of preventing and treating liver cancer by inhibiting the activity of RR of liver cancer cells, including the RR activity activated by HBV to inhibit proliferation of liver cancer cells, and achieve the aim of treating various tumors by inhibiting the RR. The 4-hydroxy salicylamide can be used for preventing and treating hepatitis B, liver cancer, oropharyngeal epithelioma, colorectal cancer, ovarian cancer, non-small cell lung cancer, chronic myeloid leukemia and other tumors, and has important application prospect.

Methods of reducing hepatitis delta virus (HDV) viral loads in a patient are provided. In some embodiments, the method comprises treating the patient with lonafarnib-ritonavir co-therapy. In some embodiments, the method further comprises treating the patient with an interferon.

The invention relates to a medicinal composition for treating severe hepatitis which comprises the active constituents of oriental wormwood 30g, cape jasmine 20g, yellow-corktree bark 20g, baikal skullcap root 15g, oriental water plantain rhizome 20g, radix paeoniae rubrathe 50g, root of red rooted saliva 30g, curcuma aromatica 20g, root of herbaceous peony 30g, fruit of barbary wolf berry 15g, prepared rhizome of rehmannia 30g, schisandra fruit 15g, cornus officinalis 10g, creeping euphorbia 30g, Chinese dates 15g, licorice root 5g and notoginseng powder 3g.

A method of monitoring worsening of hepatitis characterized by comprising assaying GPC3 with the use of an antibody which recognizes the GPC 3N end. According to this method, worsening of hepatitis, namely, progress of hepatitis or cirrhosis toward liver cancer can be presumed.

The Chinese medicine for curing hepatitis B is made of 6 Chinese medicinal materials of black vitriol, cinnabar, capillaris, gardenia fruit, flying squirrel's droppings, cucumber gourd seed and edible vinegar. It can be made into various dosage forms of pill preparation, powder perparation and oral liquor. Its effective rate is 98% and cure rate is above 60%, and it has no toxic side efect.

A Chinese traditional medicine for curing acute viral hepatitis belongs to a Chinese traditional medicine for curing hepatitis. The ingredients of the medicine are 30g of red peony roots, 30g of bushy knotweed roots, 30g of hedyotis, 30g of china smilax roots, 30g of glabrous greenbrier rhizome, 40g of coix seeds, 20g of roots of red salvia, 10g of fresh Chinese rhubarb and 10g of purple gromwell roots; the auxiliary ingredients are 15g of virgate wormwood herb and 15g of gardenia under the situation of being obviously hot and damp; 20g of sodium sulfate and 20g of immature orange fruit under the situation of obstructed hollow viscera; 25g of moutan bark and 25g of gentian roots under the situation of exuberant epidemic toxin; 16g of bile arisaema and 16g of white mustard seeds under the situation of syndrome of accumulated turbid phlegm; 10g of dried green orange peel and 10g of curcuma roots under the situation of qi stasis. The dispensation materials in the prescription are all natural Chinese traditional medicines and the Chinese traditional medicine is manufactured with the traditional processing method; moreover, the materials are easy and the prescription and manufacture method are simple and the cost for manufacturing medicine is low. The composition of the Chinese herbal medicine is simple and the medicines used in the prescription are all natural ones and the fetching and use are convenient; the manufacture method is simple and the effect is excellent; the price is low; in this way, the herbal medicine is especially fit for people living in remote villages far away from counties and towns; the curing expense for patients with the disease of acute viral hepatitis is low which solves the problem that the household income is low and the life is poor and the medical conditions is deficient locally.