The invention discloses a soft close-fitting intelligent health monitoring vest, and belongs to the field of health monitoring equipment. The scheme includes that a flexible printed circuit board is arranged at a front chest of a vest body, a sensor module, a control core device and a key module are arranged on the flexible printed circuit board, the sensor module which is in contact with the skins of a wearer is provided with non-sticky conductive rubber jackets, and portions, except for the sensor module, of the flexible printed circuit board are in contact with the skins of the wearer via lint after being insulated and isolated; the sensor module is used for monitoring electrocardiogram signals, heart and lung sound signals and body temperature signals and transmitting the electrocardiogram signals, the heart and lung sound signals and the body temperature signals to the control core device; external instruments can be transmitted to the control core device by the key module; data can be exchanged between the control core device and a mobile phone in a wireless mode, can be uploaded to a cloud data management system by the mobile phone and can be called by doctors or users or family members. The soft close-fitting intelligent health monitoring vest has the advantages that the soft close-fitting intelligent health monitoring vest which is an intelligent health monitoring garment can be used by old people, old people can wear the intelligent health monitoring garment comfortably, influence on normal life can be prevented, and the intelligent health monitoring garment is free of maintenance or complicated operation; the vest is used for monitoring the health of old and weak people.