37 results about "Parathyroid Tetany" patented technology

The invention belongs to the field of medicinal chemistry, and particularly relates to a novel crystalline form A of doxercalciferol and a preparation method for the novel crystalline form A. The invention further comprises a pharmaceutical composition of the novel crystalline form A of doxercalciferol and an application of the composition for treating osteoporosis or secondary hyperparathyroidism. By virtue of Cu-Kalpha radiation, X-ray powder diffraction has diffraction peaks at positions where 2theta angles are 7.82, 8.51, 12.06, 13.01, 15.60, 17.05, 17.82, 18.71, 19.35, 20.06, 20.37, 20.62, 21.98, 22.68, 22.90, 23.81 and 24.79. The invention further discloses a technically improved scheme for preparing high purity doxercalciferol at the same time. The scheme is simple in step, easy to operate, short in consumed time and low in cost, and industrial large-scaled production is quite facilitated.

The present invention provides a dihydropyridazine-3,5-dione derivative or a salt thereof, or a solvate of the compound or the salt, a pharmaceutical drug, a pharmaceutical composition, a sodium-dependent phosphate transporter inhibitor, and a preventive and/or therapeutic agent for hyperphosphatemia, secondary hyperparathyroidism, chronic renal failure, chronic kidney disease, and arteriosclerosis associated with vascular calcification comprising the compound as an active ingredient, and a method for prevention and/or treatment.

The invention discloses a method and a system for identifying parathyroid hyperplasia in an ultrasonic image. The method comprises the following steps: acquiring a training sample comprising the ultrasonic image and a corresponding diagnosis result, wherein the ultrasonic image is an image obtained after ultrasonic imaging is carried out on a hyperparathyroidism area of a patient; carrying out data enhancement processing on the training sample by adopting a mixed gamma-CLAHE method; inputting the enhanced training sample into a Faster R-CNN network to obtain a trained network model; and inputting the neck ultrasonic image to be recognized into the trained Faster R-CNN model to obtain a recognition result output by the trained model. The method is high in recognition accuracy and high in speed, can help doctors to quickly find out organ positions and judge organ possibility from the perspective of image recognition, and improves efficiency for the doctors.

The invention relates to application of a molecular marker in diagnosing of parathyroid tumor, in particular to application of one or more combination parts which are selectively combined to the molecular marker in preparation of a reagent for authenticating the parathyroid tumor. The molecular marker is selected from CD24, HMOX1, VCAM1 or KCNA3.

The invention discloses an accurate intraoperative parathyroid gland recognition method and a detection device thereof. The detection device comprises a No. 22 needle, a 5ML sterile injector, a glassslide, a shell, a digital display angle gauge, a micro stepping motor, a rotating shaft, a gear, a sliding groove, a first clamping groove, a sliding plate, a rack, a first travel switch, a second travel switch, a second clamping groove, a close cover, a first switch, a second switch and a storage battery. The accurate intraoperative parathyroid gland recognition method and the detection device thereof have the advantages that by the angle detection and display device, accuracy of inclined puncture angles can be improved, and follow-up extraction success rate can be increased; by an internal electric pumping mechanism, operation of medical workers is facilitated and high efficiency in pumping is improved; through coordination between multiple clamping grooves and limiting and fixing devices, the detection device can be used with the 5ML sterile injector in the prior art, and an electric mechanism can be reused sterilely; operation burdens of the medical workers are relieved, detectioncost is reduced, and clinical popularization and application are benefited.

The present invention includes an oral pharmaceutical capsule comprising a shell, lanthanum carbonate or lanthanum carbonate hydrate, and a lubricant such as talc, wherein the shell encapsulates the lanthanum carbonate or lanthanum hydrate and the lubricant. Capsule shells comprise, for example, gelatin. The capsules of the present invention dissolve at a similar rate before and after storage. The oral pharmaceutical capsules of the present invention can be administered to treat a patient at risk for or suffering from hyperphosphatemia, at risk for or suffering from chronic kidney disease (CKD), at risk for or suffering from soft tissue calcification associated with CKD, or at risk for or suffering from secondary hyperparathyroidism.

The invention provides a preparation method of a falecalcitriol tablet, and belongs to the technical field of medicines. The falecalcitriol tablet disclosed by the invention is prepared from falecalcitriol, a sustained-release material, a filling agent, a lubricating agent and a 95% ethanol solution. The main component of the pharmaceutical composition is falecalcitriol which belongs to vitamin D3analogues, can regulate calcium metabolism and resist rickets, and is used for treating parathyroid hypofunction. The method provides a sustained-release preparation which is safe, effective, stablein quality, low in cost, low in administration frequency, high in patient compliance and capable of slowly releasing drugs.

The invention discloses a parathyroid detection method. The method involves an operating bed, an equipment table and a handle probe, and further involves a transmitting optical fiber, a detection optical fiber and a pedal switch, wherein the equipment table is assembled on one side of the operating bed, an integrated display is assembled on the top of the equipment table, a complete set of controller is assembled on the back of the integrated display, a main controller is arranged at the bottom of the integrated display through a bolt, the handle probe is assembled on one side of the complete set of controller through a wire, a probe is arranged at the detection end of the handle probe, the transmitting optical fiber and the detection optical fiber are inserted into the end of the probe, a near-infrared camera is arranged on the probe through a bolt, the probing and shooting end of the near-infrared camera is connected with the tail end of the detection optical fiber, and a probe switch is assembled on the handle probe. According to the method, by means of an infrared imaging instrument, the confidence of a surgeon on parathyroid identification is obviously improved, the operation time is shortened to a certain degree, the operation difficulty is reduced, and fine operation in an operation is well facilitated.

The invention discloses a side gland surgical treatment auxiliary detection method, which comprises an operating bed, an equipment table and a handle probe, and further comprises a transmitting optical fiber, a detection optical fiber and a pedal switch, the equipment table is assembled on one side of the operating bed, an integrated display is assembled on the top of the equipment table, and a complete set of controller is assembled on the back of the integrated display. A main controller is arranged at the bottom of the integrated display through bolts, a handle probe is assembled on one side of the controller set through a wire, a probe is arranged at the detection end of the handle probe, a transmitting optical fiber and a detection optical fiber are inserted into the end of the probe, a near-infrared camera is installed on the probe through bolts, and a camera is installed on the near-infrared camera. The probing and shooting end of the near-infrared camera is connected with the tail end of the detection optical fiber, and a probe switch is assembled on the handle probe. By means of the infrared imaging instrument, the confidence of a surgeon on parathyroid gland identification is obviously improved, the operation time is shortened to a certain degree, the operation difficulty is reduced, and fine operation in an operation is better facilitated.

The invention relates to the technical field of biological medicines, in particular to a parathyroid carcinoma related gene mutation site and a diagnosis product thereof. The invention discloses the gene mutation site for diagnosing parathyroid carcinoma and application of the gene mutation site in preparation of a parathyroid carcinoma diagnostic reagent or kit. By adopting the kit prepared by the invention, the accuracy of early diagnosis of clinical parathyroid carcinoma can be improved, so that a patient can obtain more accurate treatment measures, and a better treatment effect is obtained. Meanwhile, a new direction is provided for a drug target for early prevention and treatment of parathyroid carcinoma, and research and development of innovative drugs are promoted.

The invention discloses a parathyroid gland probe which comprises a probe box, a detection probe rod and a detection head and further comprises a detection controller and a main controller, the detection probe rod is provided with the probe box, a detection connector is arranged at the bottom end of the detection probe rod, the detection head is assembled at the bottom of the detection connector and comprises a head sleeve and a detection core, the detection core comprises a lower mounting head, an upper mounting head, a transmitting fiber and a receiving fiber, the two ends of the transmitting fiber and the two ends of the receiving fiber are inserted into the lower mounting head and the upper mounting head respectively, a detection controller is assembled in the detection probe rod, the detection controller comprises an auxiliary processor, a modulator, a demodulator, a near-infrared camera, a laser transmitter and a battery, the detection controller further comprises a storage module and a transmission module, and a main controller is assembled in the probe box. The parathyroid gland probe is simple to operate and convenient to carry, facilitates more efficient positioning of parathyroid gland pathological areas by medical staff, and greatly improves the efficiency and success probability of parathyroid gland treatment.