The invention relates to the technical field of medical instruments, in particular to medical ozone therapeutic apparatus. The medical ozone therapeutic apparatus comprises a box and a base, wherein an air purifier, an oxygenerator, an ozone generator, an ozone processor, a mixed generator and a cleaner are arranged in the box, the air purifier and an air connector are connected, the air purifierand the ozone generator are connected with the oxygenerator, an oxygen concentration sensor and a reflux pipe are sequentially arranged on a pipeline between the oxygenerator and the ozone generator,the ozone generator is connected with the ozone processor through a three-way pipe, a valve and an ozone flowmeter are arranged on the three-way pipe, the cleaner and a waste liquid collecting tank are connected with the mixed generator, a water storage tank is arranged on the top surface of the box, and a therapeutic device connected with a mixer is arranged on the side surface of the box. According to the medical ozone therapeutic apparatus, through the air purifier and the oxygenerator, continuous supply of the ozone generator is achieved, through the oxygen concentration sensor and the reflux pipe, the concentration of supplied oxygen is ensured, and through the cleaner, the interior of the mixed generator is cleaned.