The invention discloses a special full-automatic intelligent pesticide sprayer for garden pest control, which comprises a mobile vehicle body, the lower surface of the mobile vehicle body is fixedly connected with two first plates and two second plates, and the first plates and the second plates are provided with through holes and are rotatably connected with first shafts driven by a power mechanism to rotate through fixed shafts of the through holes; the two ends of the first shaft are fixedly connected with rolling wheels, the surfaces of the first shafts on the second plates are fixedly sleeved with incomplete bevel gears, and the sides, away from the first plates, of the two second plates are fixedly connected with third plates. According to the agricultural pesticide spraying device, through cooperative use of the structures, the problem that in the actual use process, due to small-range agricultural pesticide spraying, manual carrying of a small pesticide spraying machine is mostly adopted for local-range pesticide spraying is solved; the problems that in the prior art, time and labor are wasted in use, efficiency is low, sufficient pest control operation is difficult to conduct on plants in a garden in a large range, and inconvenience is brought to use are solved.