The invention discloses a hydropower station monitoring system guide vane opening analog quantity segmented open-loop control and speed regulator PID closed-loop control combined control method and system. The hydropower station monitoring system guide vane opening analog quantity segmented open-loop control and speed regulator PID closed-loop control combined control method is based on a water head, active power and guide vane opening corresponding data table, in an opening mode, a monitoring system adopts a mode of looking up the corresponding data table and segmented open-loop control, a guide vane opening degree analog quantity control signal is output, a speed adjusting system adopts a PID closed-loop control mode, a hydraulic servo system control signal is output, the guide vane opening degree analog quantity control signal and the hydraulic servo system control signal are combined to quickly and accurately adjusting the active power of a unit, the problems that a power closed-loop conventional pulse adjusting mode is adopted in an opening degree mode, the active power adjusting speed is low, the adjusting process is easily influenced by the water hammer reaction and the unitinertia effect, in a pure open-loop control mode, consequently static deviation exists in opening degree control due to the fact that the water head, active power and guide vane opening degree corresponding data table have deviation are solved, and meanwhile, the serious overshoot phenomenon caused by the excessively-high adjusting speed is restrained.