The present invention relates to a surgical instrument platform including a base, an adjusting assembly and an instrument assembly. The adjusting assembly is disposed on the base and is composed of amechanical arm; and the instrument assembly includes a surgical instrument and an instrument platform, the surgical instrument is detachably disposed on the instrument platform, the instrument platform is connected with the end of the mechanical arm, the surgical instrument includes an operation end, a connecting assembly and an end executor connected in sequence as well as a sensing component, adriving component, a transmission component and a control component, wherein the connecting assembly includes a first connecting structure and a second connecting structure, the near end of the firstconnecting structure is connected with the operation end, the far end of the first connecting structure is connected with the instrument platform, the far end of the second connecting structure is connected with the end executor, and the near end of the second connecting structure is connected with the instrument platform. The sensing component detects the movement of the first connecting structure, and the control component controls the driving component to drive the second connecting structure to move by virtue of the transmission component according to the movement of the first connecting structure. The surgical instrument platform has the advantages of higher precision and reliability as well as labor saving and convenience in surgery operation.