The invention discloses a full-automatic tissue packaging machine, and belongs to the field of packaging machines. The full-automatic tissue packaging machine comprises a feeding device, a packaging forming device and a bag making device, wherein the outlet end of the feeding device corresponds to a packaging inlet of the packaging forming device, the bag making device conveys packaging bags to the position between the outlet end of the feeding device and the packaging inlet of the packaging forming device, and the feeding device comprises a material arranging mechanism, a material clamping mechanism and a material pushing mechanism. According to the full-automatic tissue packaging machine, equipment for the processes such as feeding, bag making and packaging forming are integrated into awhole, so that the structure is compact, and the occupied space is saved; and meanwhile, the steps of automatic material arranging, automatic material clamping, automatic material pushing and the likecan be carried out, and manual intervention is not needed, so that the automation degree is higher, the labor cost is reduced, better cleanness and sanitation are achieved, and the packaging qualityand the packaging efficiency are improved.