38results about How to "Solve the greater risk" patented technology

This invention is directed to an improved method for preventing deposition residue buildup on the internal surfaces of an ALD reactor chamber. In an ALD deposition process, the surfaces of a substrate are treated with an initiating precursor generating a labile atom reactive with a deposition precursor. Excess initiating precursor is removed from the reactor and the substrate surface then is exposed to a deposition precursor reactive with the labile atom under conditions for generating a fugitive reaction product containing the labile atom and leaving a deposition product. The process is repeated generating alternate layers of initiation and deposition precursor reaction products. The improvement in the ALD process resides in passivating the internal surfaces of the reactor by removing labile atoms reactable with either the initiating or deposition precursors prior to effecting ALD deposition.

A colonoscope includes an elongated body extending between a proximal and a distal end, a tip arranged on the distal end of the elongated body, and a handle arranged on the proximal end of the elongated body, wherein the elongated body generally increases in diameter and flexibility from the distal end to the proximal end. The elongated body preferably has a plurality of segments, each more proximal segment having a larger diameter than each adjacent more distal segment and/or each more proximal segment being more flexible than each adjacent more distal segment. A method for manufacturing a colonoscope includes selecting a length for each segment such that a most distal segment will extend far enough into a corresponding most distal section of the colon to be examined with each more proximal segment advanced through a corresponding more proximal section of the colon.

An oropharyngeal airway for use during diagnostic and surgical procedures, comprising a body with a proximal and a distal end. The distal end is sized for insertion through a protective bite block disposed in a patient's mouth. Both sides of the distal end are tapered to a curved distal edge. A flange is transversely opposed at the proximal end, preventing the proximal end from moving through the protective bite block and into the patient's mouth. An elliptically-arched channel in the shape of a lingual contour extends from the proximal end to the distal end. The channel includes a pair of tapered upstanding walls that guide the passage of a surgical instrument through the space between them. The oropharyngeal airway can be constructed of recyclable or biodegradable materials and is compatible with protective bite blocks of all sizes.

A combination bicycle fork and steering tube assembly is formed with a pair of downwardly directed, mutually converging end closure tabs that are bent over into abutment and welded together to define peripherally enclosed fork openings at the ends of the steerer tube. The upper ends of the hollow fork legs are configured to follow the surface contours of the lower end of the steerer tube and are welded to the end closure tabs about the circumferences of the enclosed fork openings at the lower end of the steering tube. The front wheel axle dropouts are formed directly in the lower ends of the fork legs, which include internal dropout support inserts. The dropout support inserts are sandwiched in between a pair of flat, mutually parallel dropout tabs defined directly in the lower ends of the fork legs. The preload bolt has an internal partition that defines a wrench socket that is radially displaced from the axial center of the preload bolt. A large cable routing passage is thereby created through the hollow preload bolt.

The invention relates to a thermoforming packaging machine with a top film forming station, the forming tool upper part and the forming tool lower part of which are disposed above a lower film transportation plane and via a traverse system connected to a lifting mechanism and where said lifting mechanism is disposed below said lower film transportation plane.

A method and a system are for determining of the compatibility of control software, which is designed for standard parameters, with a wind energy installation which is operated using operating parameters. The method is an automatic method in which the operating parameters of the wind energy installation and the standard parameters of the control software are first transmitted to a computation unit. The computation unit determines discrepancies between the operating parameters and the standard parameters. A decision on compatibility is made on the basis of the discrepancies. The system includes a logic module which is designed to make the decision. This method makes it easier to automatically update the control software for a wind energy installation. There is no longer any need to manually check the compatibility of the new version of the control software before the new version of the control software can be installed.

The present invention provides a method for detecting a genetic variant in a region of interest in a DNA sample comprising (i) determining, for a given sequencing platform, sequencing process and sequencing depth, the distribution of the number of reads supporting a genetic variant or plurality of genetic variants expected to be observed in the sequencing results of amplification reactions due to amplification and sequencing error (read count distribution); (ii) based on the read count distribution determined in step (i), establishing a threshold frequency at or above which the genetic variant must be observed in sequencing results of amplification reactions to assign a positive determination for the presence of the genetic variant in a given amplification reaction; (iii) partitioning the DNA sample into a plurality of replicate amplification reactions, so that the mean number of amplifiable template molecules of the region of interest in a replicate amplification reaction is fewer than the reciprocal of the threshold frequency determined in step (ii); (iv) performing the amplification reactions of step (iii) and sequencing the products of amplification reactions, (v) based on step (ii) and the results of step (iv), determining the presence/absence of the genetic variant in each replicate amplification reaction; and (vi) integrating the results of (v) to determine the presence/absence of the genetic variant in the region of interest in the DNA sample.

A battery-operated electrical tool (10) is provided with a machine housing (11) that has a longish, substantially rod-shaped housing portion (12) containing an electric drive motor (13) and an end portion (15) on which a terminal connection surface (16) with push-in receptacle (17) for the detachable attachment of a battery packet (14) is provided, which said battery packet is provided with a connection part (18) that comprises a seating surface (19) matched to the connection surface (16) for seating on said connection surface, and comprising a push-in part (20) engaging in the push-in receptacle (17). The end portion (15) is inflected toward one side in relation to the housing portion (12) out of the direction of longitudinal extension. The terminal connection surface (16) of the end portion (15) extends within a plane (21) that is oriented skew in relation to a plane (22) extending substantially perpendicularly to the longitudinal axis (23) of the housing portion (12).

A method of making a non-volatile double-gate memory cell. The gate of the control transistor is formed with a relief of a semiconductor material on a substrate. The control gate of the memory transistor is formed with a sidewall of the relief of a semiconductor material configured to store electrical charge. A first layer is deposited so as to cover the stack of layers. The first layer is etched so as to form a first pattern juxtaposed on the relief. A second layer is formed on the first pattern. The second layer is etched so as to form on the first pattern a second pattern having a substantially plane upper face.

Recombinant activated protein C (APC) and APC variants with reduced anticoagulant activity were used to reduce mortality in murine models of sepsis. These models included endotoxemia and bacteremia models. We discovered that single or multiple bolus doses of APC, especially of APC variants such as RR230/231AA-APC, KKK192-194AAA-APC and 5A-APC (containing the combination of mutations present in the first two APC variants) given as a single bolus reduces 7-day mortality of mice given lethal doses of endotoxin. Administrations of a single bolus of 5A-APC after the initiation of sepsis also reduces mortality caused by LPS. 5A-APC with ≦8% of normal anticoagulant activity (which has reduced risk of bleeding) reduces mortality when given as two bolus administrations at 3 hours and then at 10 hours after initiation of bacterial infection, i.e. after onset of sepsis. This shows, first, that one or more bolus injections of APC or of APC variants, especially 5A-APC, can reduce mortality when given beginning hours after the onset of sepsis and, second, that it is not necessary to administer APC as a continuous infusion which is the current standard of practice because one or more bolus administrations can reduce mortality. Furthermore, dosages of approximately 0.06 to 0.4 mg/kg of APC and APC variants are identified to be sufficient to reduce mortality in sepsis.

Methods of designing at least one progressive ophthalmic lens for a user having a dominant eye and a non-dominant eye are provided. These methods include determining a first inset for a lens for the dominant eye, and determining a measurement of phoria of the user. The methods further include determining a second inset for a lens for the non-dominant eye depending on the first inset and on the measurement of phoria, and designing the lens for the non-dominant eye according to the second inset. Systems, computer systems and computer program products suitable for performing these design methods are also provided. Progressive ophthalmic lenses designed according to said design methods are also provided.

A liquid discharging apparatus includes: a liquid compartment; a flowing-in passage that is in communication with the liquid compartment through a flowing-in opening, the liquid flowing through the flowing-in passage into the liquid compartment; a nozzle that is in communication with the liquid compartment through a communication opening; a capacity changer that causes the liquid contained in the liquid compartment to be discharged from the nozzle by causing a displacement of an inner wall surface of the liquid component and changing capacity of the liquid compartment; and a flowing-in passage resistance changer that changes capacity of the flowing-in passage to change flow resistance of the flowing-in passage. In the liquid compartment, as viewed from the flowing-in opening, the communication opening is located in front of a center-of-displacement portion, an amount of the displacement of which is largest in the inner wall surface displaced by the capacity changer.

A vehicle structure sub-unit includes a cross-member of metal material and two crash-box modules with their front surfaces welded or glued to the rear wall of the cross-member. A reinforcing metal plate is interposed between the front surface of at least one of the two crash-box modules and the rear wall. The rear wall has a depressed flat portion in which the reinforcing plate is received, in such a way that the surface of the reinforcing plate facing the crash-box module is substantially flush with the surface of the rear wall. A depressed portion of the rear wall is located in an offset position, closer to the center of the cross-member, with respect to the crash-box module, in such a way that the reinforcing plate is in contact only with a part of the front surface of the crash-box module, the remaining part of the front surface being in direct contact with the rear wall.