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59 results about "Ventilatory function" patented technology

Ventilators support the breathing process of critically ill patients who had lost the ability to breathe on their own. Their main functions include getting oxygen into the lungs and removing carbon dioxide from the body, aiding the respiration process. For more details Visit: Trivitron Health Care.

Visual airway clearance device with function of intelligently regulating and controlling internal and external oscillation of airway

The invention relates to a visual airway clearance device with an intelligent airway internal and external oscillation control function. The visual airway clearance device comprises an electrical impedance imaging device, a controller, an airway internal oscillation device and an airway external oscillation device. The electrical impedance imaging device is used for evaluating the lung ventilation function condition of a patient and transmitting measured lung ventilation function index parameters of the patient to the controller; the controller receives the pulmonary ventilation function index parameters of the electrical impedance imaging device, processes the pulmonary ventilation function index parameters and outputs a control signal; and after receiving the control signal, the air passage internal and external oscillation devices adjust the operation modes and parameters of the air passage internal and external oscillation devices in real time. The system has the advantages that a four-dimensional integrated structure of electrical impedance imaging visual evaluation, intelligent mode selection, double-oscillation cooperation and closed-loop feedback is created for the first time, the problem that the traditional technology cannot dynamically adapt to the heterogeneity of patients is solved, and personalized airway clearance modes and optimal adjustment parameters are provided for different patients; and the effect of removing airway deposited secretions is obvious.
Owner:THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

Abnormality identification method and device for pulmonary ventilation function examination, electronic equipment and computer storage medium

The invention provides an anomaly identification method and device for pulmonary ventilation function examination, electronic equipment and a computer storage medium. The abnormal recognition method for pulmonary ventilation function examination comprises the following steps: S1, acquiring a pulmonary ventilation function examination curve to be recognized, and processing the pulmonary ventilation function examination curve by adopting an adaptive Fourier (AFD) method; and S2, inputting the lung ventilation function examination curve obtained after processing into a trained YOLO algorithm model, wherein the YOLO algorithm model identifies abnormal conditions of the lung ventilation function examination curve. According to the abnormity identification method, the AFD technology and the deep learning technology are combined, the abnormal condition of pulmonary ventilation function examination can be efficiently and accurately identified, the reliability and consistency of examination data are ensured, medical personnel can be assisted in completing examination quality control, and the examination efficiency is improved. And the problem of insufficient training and practical experience of medical personnel in some regions and some medical institutions is effectively relieved.
Owner:MACAU UNIV OF SCI & TECH

Clinical lung function rehabilitation apparatus for respiratory medicine department

The invention relates to the technical field of lung function rehabilitation, and provides a clinical lung function rehabilitation device for the respiratory medicine department. An adjusting mechanism is installed in the movable frame, and a limiting frame is installed at one end of the adjusting mechanism; second connectors are mounted on the two sides of the respiratory training device respectively; an air delivery pipe is installed on the outer wall of the second connector, a sputum excretion mechanism is installed at one end of the air delivery pipe, the sputum excretion mechanism comprises a positive pressure exhalation device, and one end of the positive pressure exhalation device is installed at one end of the air delivery pipe. A patient breathes by holding a silica gel nozzle, so that oxygen enters a gas conveying pipe through a breathing training device 5 and then enters a positive-pressure exhalation device and a second connecting pipe, then gas enters the positive-pressure exhalation device through exhalation, the positive-pressure exhalation device generates positive pressure to keep an airway open, and the positive-pressure exhalation device is used for breathing. The device is usually used for helping expectoration and improving the lung ventilation function, and then the lung is exercised through breathing.
Owner:TAIZHOU CENT HOSPITAL

Prone position ventilation air cushion

The utility model relates to medical auxiliary appliance related technical field more, more specifically, the utility model provides prone position ventilation air cushion, including support pad body and support part, the support part sets up in support pad body, and the support part includes with the face support air cushion, shoulder support air cushion, crotch support air cushion and knee support air cushion corresponding to the position of the limb part, the face support air cushion, shoulder support air cushion, crotch support air cushion and knee support air cushion independently sets up and is respectively through the inflation conduit with the air pump intercommunication, the shoulder support air cushion and knee support air cushion respectively are equipped with phase change material in, the face support air cushion is provided with ventilation groove, is equipped with the collecting box for receiving secretion in ventilation groove, and the collecting box setting in ventilation groove is opposite the mouth part setting, is used for receiving oral cavity secretion (such as saliva), and the secretion in the collecting box is washed and collected regularly by starting negative pressure pump and water pump, avoids the secretion stagnation and influences ventilation function.
Owner:FIRST PEOPLES HOSPITAL OF NANNING

Device, method and system for detecting pulmonary ventilation function

The invention relates to the technical field of pulmonary function detection, in particular to a pulmonary ventilation function detection device, method and system. The tension degree of a subject is quantified through waveform change of an electrocardio curve and amplitude fluctuation of an arm myoelectricity curve to determine the initial tension degree; the initial tension degree is corrected according to the characteristic that tension expressions presented by an electrocardio curve and an arm myoelectricity curve during tension of the subject are consistent, and the corrected tension degree with more accurate tension degree characterization is determined; then the initial pulmonary ventilation volume time sequence curve is corrected in combination with the corrected tension degree, and the problem that the pulmonary ventilation function of the subject is not accurately measured directly according to the pulmonary ventilation volume time sequence curve of the subject in an existing pulmonary ventilation capacity test is solved; the accuracy of lung ventilation function detection according to the corrected lung ventilation volume time sequence curve is higher.
Owner:PEOPLES HOSPITAL OF INNER MONGOLIA AUTONOMOUS REGION +1

Prompt Information Generation Method and Anesthesia Airway Opening Assistance Device

ActiveCN120053834BMedical communicationRespiratorsPhysical therapyLeft lung ventilation
This application is applicable to the technical field of anesthesia airways, and particularly relates to a method for generating prompt information and an anesthesia airway opening assistance device. The method includes: obtaining hot gas information in real time; wherein, the hot gas information includes temperature data and gas flow rate transmitted by an array composed of a plurality of sensors at preset time intervals; obtaining analysis information based on the hot gas information; wherein, the analysis information includes at least one airflow obstruction index corresponding to a specific area in the user's airway and ventilation volume information, the airflow obstruction index reflects the obstruction condition of the specific area in the user's airway, and the ventilation volume information includes left lung ventilation volume and right lung ventilation volume; obtaining prompt information based on the analysis information. The method for generating prompt information provided by the embodiments of this application can improve the problem that when a patient is anesthetized, airway collapse occurs, resulting in airway obstruction and further causing ventilation dysfunction in the patient.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Anesthesia system and medical equipment

The invention relates to the field of medical apparatus and instruments, and discloses an anesthesia system and a medical device.The anesthesia system comprises a gas source module, a flow monitoring module, an anesthetic gas conveying system, a waste gas purification system, a rapid oxygenation module, a hyperbaric oxygen module, a negative pressure suction system, a manual control module and an auxiliary ventilation branch; the anesthetic gas conveying system provides anesthetic support and first respiratory support for a patient, the rapid oxygenation module provides second respiratory support for the patient, the air inlet end of the auxiliary ventilation branch is connected with the flow monitoring module, the air outlet end of the auxiliary ventilation branch is connected with the inspiration branch, and third respiratory support is provided for the patient. Various ventilation functions are integrated together, the application range of the anesthesia system can be expanded, use of extra equipment is reduced, the burden of a user is relieved, meanwhile, the auxiliary ventilation branch and an original anesthesia gas path share the flow adjusting, monitoring and oxygen concentration monitoring functions, the gas path structure is simplified, the cost of the anesthesia system is reduced, and the workload of the user is relieved.
Owner:NANJING WEITAI MEDICAL TECHNOLOGY CO LTD

Method for assembling a multifunctional tube and multifunctional tube

The present application relates to a kind of multifunctional pipeline assembly method and multifunctional pipeline, belong to composite precision forming technical field, solve the single function of existing pipeline, the pipeline of ventilation pipeline and electric signal is set apart, cannot satisfy the use demand in narrow cabin problem.The assembly method of the multifunctional pipeline, comprising the following steps: step 1: connecting the gas path main body with the connecting seat, obtain gas path assembly;Step 2: the insulation part is set in the outside of thermocouple, and thermocouple is fixed on the connecting seat;Step 3: sleeve assembly is set in the outside of gas path main body and thermocouple;Step 4: connecting the gas path main body with the pipe mouth;Step 5: the free end of thermocouple is connected with electric connector, obtain multifunctional pipeline.The present application realizes the diversification of pipeline function, a pipeline has both ventilation function, and has electric function.
Owner:BEIJING XINGHANG MECHANICAL ELECTRICAL EQUIP CO LTD

Opening and closing type pre-coating plate

The invention discloses a precoating plate capable of being opened and closed. The precoating plate comprises a precoating plate body, an opening and closing block, a transmission assembly and a control mechanism. A control mechanism can drive a moving plate to move front and back, when the moving plate moves towards the outer side, the moving plate drives a plurality of opening and closing blocks to move towards the outer side through a transmission rod, an opening groove is opened, meanwhile, the moving plate drives a plurality of closing plates to move towards the outer side through a connecting rod, and a plurality of through holes are opened; in this way, the inner side of the pre-coating plate body is ventilated, and a wall abutting against the inner side of the pre-coating plate body has a ventilation function; when the moving plate moves towards the inner side, the moving plate drives the opening and closing blocks to move towards the inner side through the transmission rods, the opening and closing blocks are in butt joint with the opening grooves, meanwhile, the moving plate drives the closing plates to move towards the inner side through the connecting rods, and the closing plates abut against the through holes in a closed mode, so that structural resetting is achieved, and structural stability and integrity are achieved.
Owner:JIANGSU JUNAN NEW MATERIAL SCI & TECH CO LTD

Lung ventilation function measuring method and device based on smartphone microphone

The invention belongs to the field of artificial intelligence and non-contact measurement, and relates to a lung ventilation function measurement method and device based on a smartphone microphone. A built-in microphone of the smart phone is used for collecting breathing audio signals of a user in the measurement process, and a lung ventilation function true value is obtained through the lung function instrument to serve as reference data; dividing an inspiration phase and an expiration phase of the breathing audio signal based on a threshold method, and extracting an expiration phase audio clip; processing the expiration signal by using a self-adaptive convolution frequency domain enhancement network, dynamically adjusting a convolution kernel to adapt to different frequency bands by self-adaptive convolution, and enhancing low-frequency components by combining frequency domain enhancement with fast Fourier transform; the transformation type convolutional network models time sequence dependence through causal convolution and jump convolution, and the feature learning ability is enhanced through residual connection and dense connection; and finally predicting lung ventilation function parameters through full connection layer regression. According to the invention, the accuracy of lung ventilation function measurement based on the microphone of the smart phone is improved, and the user can conveniently carry out self-health monitoring.
Owner:DALIAN UNIV OF TECH

Lung segment function evaluation method based on drainage basin characteristics

The invention relates to the technical field of medical image processing, in particular to a lung segment function evaluation method based on drainage basin characteristics, which comprises the following steps: acquiring medical image data of a lung; based on the medical image data, constructing a digital model of a lung blood vessel network and an airway network; calculating network features of the pulmonary vessel network and the airway network based on the digital model; generating a blood supply function score and a ventilation function score according to the network features; calculating a comprehensive function score based on the blood supply function score and the ventilation function score; according to the method, the characteristics of the pulmonary vascular network and the airway network are comprehensively analyzed, advanced network analysis and machine learning technologies are combined, multi-dimensional evaluation of the pulmonary segment function is achieved, digital models of the pulmonary vascular network and the airway network are constructed, and the pulmonary segment function evaluation accuracy is improved. And then comprehensively describing the characteristics of the lung structure by calculating a series of network characteristics, such as centrality, efficiency and density.
Owner:GUANGDONG GENERAL HOSPITAL

Invasive and noninvasive dual-purpose breathing equipment for respiratory tract sepsis

InactiveCN121623087ATracheal tubesTracheostomy deviceVentilatory function
The invention discloses invasive and noninvasive respiratory tract sepsis dual-purpose breathing equipment, and belongs to the technical field of medical instruments, the breathing equipment comprises a tracheostomy cannula and an air source assembly, the starting end of the tracheostomy cannula is used for being inserted into the trachea of a tracheostomy patient, the tail end of the tracheostomy cannula is located outside the neck of the patient, and the tail end of the tracheostomy cannula is provided with a speaking assembly; the tracheostomy device further comprises a tracheostomy mask which can cover the wound of the neck of the patient. The breathing equipment is provided with a first mode and a second mode; when the breathing equipment is in a first mode, the tracheostomy cannula is connected with the speaking assembly, and the tracheostomy mask is connected with the air source assembly; and when the breathing equipment is in the second mode, the tracheostomy tube is connected with the air source assembly. The first-mode invasive ventilation function and the second-mode non-invasive ventilation and sound production function are integrated into one set of equipment, so that multiple functions are integrated, medical staff do not need to prepare different equipment for different modes, and clinical management is simplified.
Owner:KUNMING YANAN HOSPITAL (KUNMING CADRE NURSING HOME)

A nebulizer inhalation device for the department of respiratory medicine

The present invention provides a nebulization inhalation device for the department of respiratory medicine, belonging to the technical field of medical devices. It includes an inhalation part and a nebulization cylinder. The inhalation part and the nebulization cylinder are detachably connected through a first connecting pipe body and a second connecting pipe body. The first connecting pipe body is fixedly installed at the air delivery end of the nebulization cylinder, and the second connecting pipe body is fixedly installed at the air delivery end of the inhalation part. A partition part and an opening mechanism are arranged on the inner surface of the second connecting pipe body, and the partition part has toughness. By arranging a partition part inside the second connecting pipe body on the surfaces of the inhalation mask and the mouthpiece, and through the cooperation of the opening mechanism and the removal mechanism, the state of the partition part changes before and after nebulization treatment. That is, when the first connecting pipe body and the second connecting pipe body are removed after the nebulization treatment is over, the partition part can block the second connecting pipe body, causing the second connecting pipe body to lose its ventilation function, thereby avoiding the repeated use of the inhalation mask and the mouthpiece.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Cardiopulmonary rehabilitation training device for assisting chest expanding exercise

InactiveCN120168291AChiropractic devicesNursing bedsCardiopulmonary rehabilitationPhysical medicine and rehabilitation
The invention relates to the technical field of cardiopulmonary rehabilitation training devices, and discloses a cardiopulmonary rehabilitation training device for assisting chest-expanding exercise, which comprises a bed board, two arm grooves, a left arm groove, a right arm groove, a left arm groove and a right arm groove, the two arm bearing plates are movably arranged in the two arm grooves respectively; a telescopic plate is movably arranged at the tail end of the arm bearing plate in a telescopic mode, and a handle is fixedly installed at the tail end of the telescopic plate. The arm bearing plate can rotate around a virtual center, and the virtual center is the shoulder joint of the patient. According to the cardiopulmonary rehabilitation training device for assisting the chest expanding exercise, the arms of a patient are allowed to be fully unfolded backwards, the problem that the arms of the patient cannot be completely unfolded due to bed limitation of existing equipment is solved, the thorax can be effectively expanded, the gas exchange and ventilation functions of the lung are improved, and the cardiopulmonary health of the patient is improved.
Owner:CHANGZHOU TCM HOSPITAL

One-way valve, ventilation mechanism, ventilation insole and sole

A one-way valve, a ventilation mechanism, a ventilation insole and a sole relate to the technical field of shoe structures. The one-way valve comprises a valve body, an air inlet hole is provided at the air inlet end of the valve body, a flat mouth is provided at the air outlet end of the valve body, a flow guide is provided at the air outlet end of the flat mouth, and a gap is left between the flow guide and the flat mouth; the air entering through the air inlet hole can flow to the other end of the one-way valve through the valve body, the flat mouth, the gap between the flow guide and the flat mouth, and when the airflow flows in the reverse direction, the air flowing directly to the flat mouth can be diverted to both sides of the flat mouth under the action of the flow guide, so that the flat mouth is closed by the pressure of the airflow. The present invention is provided with a normally open flat mouth for normal air intake, and when exhausting, the flat mouth can be flattened and closed under the action of the airflow pressure to prevent gas from flowing out, thereby realizing a one-way ventilation function, and at the same time the flow guide can prevent the reverse airflow from rushing directly into the flat mouth and affecting its normal closure. The present invention is not only simple in structure, low in failure rate, and more durable, but also easy to implement.
Owner:HENGYANG QISHENG TECH DEV CO LTD

Application of LSH detection reagent in preparation of chronic obstructive pulmonary disease diagnosis preparation and application of LSH overexpression reagent in preparation of chronic obstructive pulmonary disease treatment medicine

The invention discloses application of a reagent for detecting LSH in preparation of a chronic obstructive pulmonary disease diagnosis preparation and application of a reagent for overexpressing the LSH in preparation of a medicine for treating the chronic obstructive pulmonary disease. Protein expression of LSH in a patient suffering from the chronic obstructive pulmonary disease is found to be lower than that of healthy people and expression of pure smokers through western blot and RT-qPCR detection for the first time. Therefore, the possibility of using the LSH as the detection marker of the chronic obstructive pulmonary disease is provided. The LSH overexpression adeno-associated virus improves obstructive ventilation dysfunction and large and small airway dysfunction of a model mouse, relieves the emphysema degree, reduces the airway inflammation level and inhibits small airway remodeling, and further analysis on inflammatory cells in the lung shows that the overexpression of the LSH overexpression adeno-associated virus can reduce the proportion of pulmonary interstitial macrophages. The invention provides a new way with a prospect for treating the chronic obstructive pulmonary disease.
Owner:THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV

Atomization image analysis method for pulmonary ventilation function evaluation

The invention relates to the technical field of lung function evaluation, in particular to an atomization image analysis method for lung ventilation function evaluation. The method comprises the following steps: firstly, acquiring lung atomization images under various concentrations by changing the concentration of aerosol; based on image block level analysis, the lung is divided into different functional regions (such as lung lobe and airway regions), particle distribution difference characteristics of different image blocks are compared to quantify deposition indexes, and regional ventilation uniformity is reflected; sub-regions are further divided in combination with density clustering, the number change of atomized particles is analyzed across time points, and a metabolic rate index is calculated to represent local metabolic activity; and finally fusing the deposition index and the metabolic rate index to generate a ventilation obstruction evaluation value. According to the method, through space-time sequence multi-parameter coupling, the breathing mode and individual difference interference are effectively reduced, the ventilation function and the metabolism state are synchronously analyzed, a quantitative basis is provided for pulmonary ventilation disorder analysis, and evaluation comprehensiveness and clinical decision accuracy are remarkably improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAN MEDICAL UNIV

Aerosol inhalation equipment for respiratory medicine department

The invention provides aerosol inhalation equipment for the respiratory medicine department, and belongs to the technical field of medical instruments. Comprising an inhalation piece and an atomization cylinder, the inhalation piece and the atomization cylinder are detachably connected through a first connecting pipe body and a second connecting pipe body, the first connecting pipe body is fixedly installed at the gas conveying end of the atomization cylinder, and the second connecting pipe body is fixedly installed at the gas conveying end of the inhalation piece; a blocking part and an opening mechanism are arranged on the inner surface of the second connecting pipe body, and the blocking part has toughness. The blocking part is arranged in the portion, on the surface of the inhalation mask and the surface of the mouth holding device, of the second connecting pipe body, and the opening mechanism is arranged to be matched with the dismounting mechanism, so that the state of the blocking part is changed before and after nebulization treatment, that is, the nebulization treatment is finished, and when the first connecting pipe body and the second connecting pipe body are dismounted, the nebulization treatment is completed. The blocking part can block the second connecting pipe body, so that the second connecting pipe body loses the ventilation function, and repeated use of the inhalation mask and the buccal device is avoided.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Lung segment function evaluation method based on basin characteristics

The present invention relates to the technical field of medical image processing. More specifically, it relates to a method for evaluating lung segment function based on watershed characteristics, including: obtaining medical image data of the lungs; constructing digital models of the pulmonary vascular network and the airway network based on the medical image data; calculating the network characteristics of the pulmonary vascular network and the airway network based on the digital models; generating a blood supply function score and a ventilation function score according to the network characteristics; calculating a comprehensive function score based on the blood supply function score and the ventilation function score; and outputting the comprehensive function score as the evaluation result of the lung segment function. The method of the present invention realizes the multi-dimensional evaluation of the lung segment function by comprehensively analyzing the characteristics of the pulmonary vascular network and the airway network, combining advanced network analysis and machine learning techniques, constructing digital models of the pulmonary blood vessels and airways, and then comprehensively characterizing the characteristics of the lung structure by calculating a series of network characteristics, such as centrality, efficiency, and density.
Owner:GUANGDONG GENERAL HOSPITAL

Transmission device and method for assisting small animals in autonomously breathing hyperpolarized gas

The invention discloses a transmission device for assisting a small animal to autonomously breathe hyperpolarized gas, which is characterized in that a sealed breathing mask is used for replacing a trachea cannula, and stable pressure of atmospheric pressure at the breathing mask is used for replacing periodic pressure change under high-pressure forced ventilation at the cannula; the animal spontaneous respiration gas amount is used for replacing the manually set fixed gas amount, and the state of inhaled gas is controlled under spontaneous respiration to replace fully controlled mechanical ventilation in the respiration process; the invention further discloses a method for assisting the small animal in autonomously breathing the hyperpolarized gas, the device can supply the gas amount required by autonomously breathing to the experimental animal according to the self-breathing state of the experimental animal, and the gas amount inhaled by the experimental animal each time is determined by the self-breathing state, so that the experimental animal can autonomously breathe in a free state; lung expansion in an abnormal breathing state can be avoided, so that a more accurate ventilation function and qi-blood exchange function evaluation result is obtained.
Owner:INNOVATION ACAD FOR PRECISION MEASUREMENT SCI & TECH CAS

A CT ventilation function imaging method based on unsupervised learning

ActiveCN114387314BReal-time imaging of ventilation functionAutomated ImagingImage analysisBiological modelsVENTILATORY FUNCTIONSFunctional imaging
The present invention provides a CT ventilation function imaging method based on unsupervised learning. Based on a convolutional neural network, an unsupervised registration module and a ventilation function imaging module are constructed, and the two constitute a CT ventilation function imaging network; an unsupervised loss function is constructed; a training set is prepared, and lung CT images of multiple subjects in two different respiratory states are used as input, and the CT ventilation function imaging network is unsupervisedly trained without any labels. CT ventilation function imaging is performed on a new subject, and the lung CT images of the new subject in two different respiratory states are input into the trained CT ventilation function imaging network, and the ventilation function image of the subject can be automatically output within a few seconds. The present invention can quickly realize ventilation function imaging of the subject, and is used for real-time evaluation of the local and overall ventilation function of the subject.
Owner:INNOVATION ACAD FOR PRECISION MEASUREMENT SCI & TECH CAS

Surgical kit, catheter and aspirator used in same

The inventions relate to medical equipment and characterize a ventilated ozonizing drainage and lavage kit, and a drainage catheter, an aspirator and an ozonator contained in said kit, as well as a method for the prophylaxis and treatment of destructive inflammatory processes. The inventions are intended to provide reliable thorough long-term atraumatic active and passive drainage, as well as ease of use.
Owner:OREKHOVSKII IGORʹ SEMENOVICH

Application of Nanovesicles from Bulbus Lilii in Radiation-induced Lung Injury as a New Radioprotective Drug

PendingCN122251516AAerosol deliveryAntinoxious agentsInflammatory factorsRadioprotective Drugs
This invention discloses the application of lily-derived nanovesicles (LDPNVs) as a novel radiation protection drug in radiation-induced lung injury, relating to the field of biomedical technology. It includes administering effective doses of lily-derived nanovesicles to subjects to prevent and alleviate radiation-induced lung injury. The LDPNVs can improve the viability and clonal survival rate of radiation-damaged lung epithelial cells at the cellular level, and alleviate pathological damage to lung tissue and improve lung function at the animal level. This invention achieves the blocking of core pathways of radiation injury, specifically downregulating the expression of key inflammatory factors, reducing lactate dehydrogenase release and total protein content in bronchoalveolar lavage fluid, and correcting abnormal respiratory rate and ventilatory dysfunction. It yields a novel radiation protection drug for radiation-induced lung injury that is naturally derived, stable in preparation, highly targeted, and has a definite protective effect, filling the application gap of plant-derived nanovesicles in this field and providing a safe and effective intervention for complications of radiotherapy for thoracic tumors.
Owner:FUDAN UNIVERSITY

The application of the reagent for detecting LSH in the preparation of a preparation for diagnosing chronic obstructive pulmonary disease and the application of the reagent for overexpressing LSH in the preparation of a drug for treating chronic obstructive pulmonary disease

The application discloses application of a reagent for detecting LSH in preparation of a preparation for diagnosing chronic obstructive pulmonary disease and application of a reagent for overexpressing LSH in preparation of a medicine for treating chronic obstructive pulmonary disease. The application finds that the protein expression of LSH in a smoking chronic obstructive pulmonary disease patient is lower than that in a healthy person and a simple smoker for the first time through Western blotting and RT-qPCR detection. Therefore, the application provides a possibility for LSH as a detection marker for chronic obstructive pulmonary disease. The application improves the obstructive ventilation dysfunction of a model mouse and the function disorder of large and small airways, reduces the degree of pulmonary emphysema, reduces the airway inflammation level and inhibits small airway remodeling through LSH overexpression adeno-associated virus, and further analysis of inflammatory cells in the lung finds that the overexpression can reduce the proportion of pulmonary interstitial macrophages. The application provides a promising new way for the treatment of chronic obstructive pulmonary disease.
Owner:THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV

Lung function diagnosis and prediction system of improved random forest model based on weighted regularization information gain

The invention relates to a lung function diagnosis and prediction system of an improved random forest model based on weighted regularization information gain, and belongs to the field of diagnosis system construction. The system comprises a data extraction module, a data preprocessing module, a feature selection module, a model training module, a diagnosis module and a result output module. The method comprises the following steps: inputting a pulmonary detection report in three forms of a text file, a PDF file and a picture file, reading each index data value in the report, training and loading a pre-trained prediction model, respectively selecting indexes required for predicting a ventilation function and a dispersion function, and inputting the indexes into the corresponding models for prediction. And finally, storing the diagnosis conclusion into a new file as a complete diagnosis report. According to the method, the SMOTE algorithm is adopted to perform up-sampling on minority class samples, so that the diagnosis accuracy and the generalization ability of the model are improved. And meanwhile, a regularization item is introduced into information gain calculation, so that an over-fitting phenomenon can be effectively prevented.
Owner:FUJIAN MEDICAL UNIV UNION HOSPITAL

A valve core for a breakaway valve and a two-way ventilation method

The present invention relates to the technical field of new energy equipment, and specifically to a valve core for a breakaway valve and a two-way ventilation method, comprising a breakaway rod, the breakaway rod being arranged in a valve body, the breakaway rod being provided with an inlet and an outlet, and the breakaway rod being provided with a normally open valve core; the normally open valve core can move relative to the breakaway rod, and the normally open valve core is used to open the flow channel in the breakaway rod when the breakaway rod is connected to the valve body, and is used to close the flow channel in the breakaway rod when the breakaway rod is separated from the valve body. The purpose is to provide a movable normally open valve core in the breakaway rod so that the breakaway valve has a two-way ventilation function, and after being broken away, the inlet and outlet can be closed separately, thereby ensuring that the inlet and outlet are closed after the two-way ventilation is broken away, and the gas will not leak out and affect the surrounding environment.
Owner:YOUPU ENERGY TECH CO LTD

Use of heparin trisaccharide compounds for the preparation of medicaments for the treatment of asthma

This invention provides the use of a trisaccharide compound with a core structure of Glc(1→4)IdoA(1→4)GlcNS in the preparation of a drug for treating or preventing asthma. This compound can reduce lung inflammation in asthma model mice, reduce mucus production in the trachea, and effectively improve ventilation.
Owner:REHABILITATION UNIV (IN PREPARATION)

Fast-assembly integrated modularized sickroom bedside equipment belt

The utility model discloses a fast-assembly integrated modularized ward bedside equipment belt which comprises an installation strip and an integrated module, the installation strip is installed on a wall face in an embedded mode, the installation strip is provided with a hollow channel, and the installation strip is provided with an air source interface and a power supply interface which are communicated with the hollow channel; the integrated module is provided with a gas connection interface, a power connection interface, a ventilation function part and a power-on function part, the ventilation function part is communicated with the gas connection interface through a pipeline, and the power-on function part is electrically connected with the power connection interface; the integrated module is detachably connected with the mounting strip, the gas connection interface is in butt joint with the gas source interface to supply gas to the ventilation function part, and the power connection interface is in butt joint with the power supply interface to supply power to the power-on function part. By adopting the arrangement, the functional modules of the equipment belt can be integrated in the integrated module and then mounted on the mounting strip, so that the equipment belt has the advantages that the mounting is convenient, and the use functions are switched and updated as required.
Owner:GUANGDONG CONSTR ENG DESIGN INST CO

Pulmonary ventilation function detection device, method and system

The present invention relates to the technical field of pulmonary function testing, and in particular to a pulmonary ventilation function testing device, method and system. The present invention quantifies the tension of a subject through waveform changes of an electrocardiogram (ECG) curve and amplitude fluctuations of an arm electromyography (EMG) curve to determine an initial tension level, and corrects the initial tension level based on the characteristic that the tension expressions presented by the ECG curve and the arm electromyography curve when the subject is nervous are consistent, thereby determining a corrected tension level that more accurately represents the tension level; and then corrects the initial pulmonary ventilation volume timing curve based on the corrected tension level, thereby solving the problem of inaccurate measurement of the pulmonary ventilation function of a subject by directly measuring the pulmonary ventilation volume timing curve of the subject in existing pulmonary ventilation tests, thereby improving the accuracy of pulmonary ventilation function testing based on the corrected pulmonary ventilation volume timing curve.
Owner:PEOPLES HOSPITAL OF INNER MONGOLIA AUTONOMOUS REGION +1