The invention discloses anti-rhagadia ointment and a preparation method thereof. The method comprises the following steps: firstly, mixing and crushing panax ginseng, angelica sinensis, zingiber officinale roscoe and Bletilla striata, soaking with an ethanol solution, and performing reflux heating; filtering, and reserving filtrate, so as to obtain a traditional Chinese medicine extract I; secondly, weighing fresh phoenix tree leaves, and performing decoction, so as to obtain phoenix tree leaf extract II; thirdly, putting the traditional Chinese medicine extract I, the phoenix tree leaf extract II, aloe vera gel and titanium dioxide into a beaker, and uniformly stirring, so as to obtain a viscous mixture III; fourthly, mixing and stirring essential oil and tea oil, so as to obtain mixed liquor IV; fifthly, pouring the mixed liquor IV, a dispersing agent and Vaseline into the viscous mixture III, and uniformly stirring, so as to obtain an ointment crude product; sixthly, performing highpressure homogenization on the ointment crude product, so as to obtain the anti-rhagadia ointment. The anti-rhagadia ointment provided by the invention not only can prevent rhagadia, but also can cure symptoms of rhagadia, further has no side effects, can still be applied to situations of rhagadia and bleeding, can achieve the effect of relieving pain and inflammation and healing wounds, and is fast to become effective and short in cure time.