39results about How to "Deterioration progress" patented technology

A photocurable resin composition for sealing an organic EL device is provided, which can seal the organic EL device without exerting any bad influence on the device, thereby suppress the formation and growth of dark spots positively, and which can ensure a high transmittance of light, thereby maintain a stable light emitting characteristic over a long period of time. The composition comprises (A) an epoxy resin containing at least two glycidyl groups in each molecule thereof and having a molecular weight of 200 to 7000, (B) an epoxy resin containing at least one glycidyl group in each molecule thereof and having a molecular weight of 20000 to 100000, (C) a latent acid photo catalyst adapted to be activated and produce an acid upon being irradiated with energy beam, and (D) a silane coupling agent containing a glycidyl group in each molecule thereof, the composition exhibiting non-fluidity at 25° C., but exhibiting fluidity in a temperature range of 50° to 100° C.

Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing or balance impairments involving neuronal damage, loss, or degeneration, preferably of spiral ganglion neurons, by administration of a therapeutically effective amount of one or more molecules having erythropoietin activity selected from EPO, or a biosimilar, a variant, or a mutant thereof; a protein or peptide mimetic of EPO; a small molecule mimetic of EPO and an erythropoiesis stimulating agent. Also provided are improved compositions and methods for treatments of ototoxicity requiring administration of a pharmaceutical having an ototoxic side-effect in combination with a therapeutically effective amount of a molecule having erythropoietin activity.

Aspects of the invention provide a method of manufacturing a luminescence device including forming the first electrode on a substrate, forming a function layer including a luminescence layer on the first electrode, forming a second electrode on the function layer, and forming a sealing layer that covers a luminescence portion, formed of the first electrode, the function layer, and the second electrode, and the sealing layer is formed by an ink-jet method. Accordingly, the deterioration of a luminescence device that is sealed with the sealing layer can be prevented for a long period of time by an inexpensive method.

A ophthalmic lens for inhibiting progression of myopia includes a central zone and an annular zone. The annular zone includes subsurface optical elements formed via laser-induced changes in refractive index of a material forming the annular zone. The subsurface optical elements are configured to modify distribution of light to the peripheral retina of a user so as to inhibit progression of myopia.

A method of preserving a harvested organ, a harvested organ tissue or a part thereof for a long time, which comprises perfusing and / or immersing the harvested organ with a solution containing HGF having a temperature of 0 to 6° C., and which method is capable of maintaining harvested organs for transplantation in a high physiological state and preventing ischemia / reperfusion injury of the organs transplanted.

There is provided a biochemical reaction cartridge comprising at least one chemical reaction chamber that accommodates a solution for biochemically treating a sample, a reaction chamber for performing detection reaction of a target substance in the biochemically treated sample, and a detection reaction information fetching section for fetching information on whether or not the detection reaction is performed, wherein the biochemical reaction cartridge is provided with a covering unit that can cover and expose at least the reaction information fetching section.

A light source device includes: a light source unit including an arc tube that emits a light between a pair of electrodes, and a reflector that reflects the light coming from the arc tube for emission of a source light; and a drive control section that drives the light source unit by a predetermined driving power. In the device, the drive control section performs power regulation control of reducing the driving power of the light source unit at a predetermined timing by a predetermined amount.

The invention analyzes relationships between factors, within a patient population, to identify autonomic dysfunction patterns. Patient test results are then compared with the identified patterns to determine the patient's autonomic function. The invention can continually amend the patient population with new test results to create increasingly accurate normative data sets from which a patient's autonomic function can be more accurately assessed. The invention may apply this concept in an application service provider model. An embodiment of the invention may use a novel method of identifying ECG R-waves. The method locates R-waves by searching for maximum slope values, in signals, that exceed threshold values. Another embodiment of the invention entails a non-provocative HRV test whereby certain time domain and frequency domain factors are analyzed to determine a patient's autonomic function.

Treating or preventing degeneration or destruction of articular cartilage and / or subchondral bone in the affected joint of a mammal is accomplished by administering a compound of formula (I), wherein the variables have the meanings given in the present description. A preferred compound of formula (I) is formula (II). This treatment ameliorates, diminishes, actively treats, reverses or prevents any injury, damage or loss of articular cartilage or subchondral bone subsequent to said early stage of said degeneration

The present invention relates to neurological and physiological dysfunction associated with neuron disorders. In (particular, the invention relates to the involvement of vascular endothelial growth factor (VEGF) and homologues in the aetiology of motor neuron disorders. The invention further concerns a novel, mutant transgenic mouse (VEGFm / m) with a homozygous deletion in the hypoxia responsive element (HRE) of the VEGF promoter which alters the hypoxic upregulation of VEGF. These mice suffer severe adult onset muscle weakness due to progressive spinal motor neuron degeneration which is reminiscent of amyotrophic lateral sclerosis (ALS)-a fatal disorder with unknown aetiology. Furthermore, the neuropathy of these mice is not caused by vascular defects, but is due to defective VEGF-mediated survival signals to motor neurons. The present invention relates in particular to the isoform VEGF165 which stimulates survival of motor neurons via binding to neuropilin-1, a receptor known to bind semaphorin-3A which is implicated in axon retraction and neuronal death, and the VEGF Receptor-2. The present invention thus relates to the usage of VEGF, in particular VEGF165, for the treatment of neuron disorders and relates, in addition, to the usage of polymorphisms in the VEGF promotor for diagnosing the latter disorders.

A photocurable resin composition for sealing an organic EL device is provided, which can seal the organic EL device without exerting any bad influence on the device, thereby suppress the formation and growth of dark spots positively, and which can ensure a high transmittance of light, thereby maintain a stable light emitting characteristic over a long period of time. The composition comprises (A) an epoxy resin containing at least two glycidyl groups in each molecule thereof and having a molecular weight of 200 to 7000, (B) an epoxy resin containing at least one glycidyl group in each molecule thereof and having a molecular weight of 20000 to 100000, (C) a latent acid photo catalyst adapted to be activated and produce an acid upon being irradiated with energy beam, and (D) a silane coupling agent containing a glycidyl group in each molecule thereof, the composition exhibiting non-fluidity at 25° C., but exhibiting fluidity in a temperature range of 50° to 100° C.

A battery lease system lends a battery to a user. The battery lease system includes a vehicle configured to be equipped with the battery for traveling, and a server that manages a lease fee to be paid by the user for lease of the battery. The vehicle permits traveling of the vehicle only for a period in which a capacity retention ratio changes by a specified amount, when the user pays the lease fee, the capacity retention ratio indicating a degree of progress of deterioration of the battery.

Provided is a terminal box for a solar cell module that has excellent heat radiation. The terminal box (10) is provided with multiple terminal boards (21), a reverse load bypass diode (22) that is connected to two corresponding terminal boards (21), a primary resin layer (23) that is attached to the diode (22) and covers the area around the diode (22), and a secondary resin layer (41) that is made from a resin different to that of the primary resin layer (23) and is adhered to parts other than the diode (22) and does not cover the area around the diode (22).

A chip antiscatter mechanism is included and configured to suppress scattering of chips generated during machining of a machining object. The chip antiscatter mechanism includes chip stirring means configured to stir the chips, by jetting a gas into a dry machining region above a table including the machining object, fluid curtain forming means configured to form a fluid curtain by jetting a fluid such as liquid or gas membranously from above to an outside of the dry machining region so as to surround the dry machining region, and to form a closed region including the dry machining region by the membranous fluid curtain, and discharging means configured to receive and discharge the fluid jetted membranously by the fluid curtain forming means.

A tire condition detecting device according to the present invention includes: an electronic component including a sensor configured to detect a tire condition; and a casing configured to house the electronic component. The casing includes a casing main body configured to house the electronic component and having an opening surface formed thereon, and a lid unit configured to cover the opening surface. An inside of the casing main body having the opening surface covered by the lid unit is filled with a sealant. Accordingly, tire conditions such as inner pressure and temperature of a tire can be surely detected and a breakdown of an electronic component can be prevented even in an environment where water content such as a coolant is injected in the tire.

There is provided a biochemical reaction cartridge comprising at least one chemical reaction chamber that accommodates a solution for biochemically treating a sample, a reaction chamber for performing detection reaction of a target substance in the biochemically treated sample, and a detection reaction information fetching section for fetching information on whether or not the detection reaction is performed, wherein the biochemical reaction cartridge is provided with a covering unit that can cover and expose at least the reaction information fetching section.

Provided is a terminal box for a solar cell module that has excellent heat radiation. The terminal box (10) is provided with multiple terminal boards (21), a reverse load bypass diode (22) that is connected to two corresponding terminal boards (21), a primary resin layer (23) that is attached to the diode (22) and covers the area around the diode (22), and a secondary resin layer (41) that is made from a resin different to that of the primary resin layer (23) and is adhered to parts other than the diode (22) and does not cover the area around the diode (22).

When a hot water supply operation is started, a single mode is used in which hot water is output only from a second hot water supply circuit of a water heater, by cut-off of a flow path in a first hot water supply circuit of a space-heating water heater by a cut-off mechanism. When a load imposed by hot water supply by the second hot water supply circuit increases during the hot water supply operation in the single mode, the cut-off mechanism is opened to start hot water output from the first hot water supply circuit and a hot water supply operation in a parallel mode is performed in which hot water is output from both of the first hot water supply circuit and the second hot water supply circuit.

A controller for a hybrid vehicle predicts whether necessary discharging electric power from a power storage device which is required to perform downshift in a transmission exceeds upper-limit discharging electric power of the power storage device when downshift in the transmission is performed in a hybrid vehicle travel mode and controls a compressor rotation speed such that a rate of increase of the compressor rotation speed of a supercharger at the time of performing downshift in the transmission increases as the upper-limit discharging electric power decreases when it is predicted that the necessary discharging electric power exceeds the upper-limit discharging electric power.

In order to keep the deterioration of water distribution pipes from progressing, a tap water management system is provided with: a water pressure detection unit for detecting the water pressure in at least one location in a water distribution pipe for carrying clean water from a water distribution site to a consumer. and transmitting the detection result as water pressure information; a deterioration detection unit for detecting deterioration in at least one location in a water distribution pipe, and transmitting the detection result as deterioration information; a water distribution planning unit for causing a water distribution plan that is a plan for water distribution pressure to be determined on the basis of information regarding past water demand; a deterioration-reducing water distribution planning unit for deciding, on the basis of the water distribution plan, the water pressure information, and the deterioration information. a deterioration-reducing water distribution plan according to the extent of deterioration; a water distribution pressure changing unit for changing the water distribution pressure of the water distribution pipe; and a water distribution pressure control unit for controlling the water distribution pressure changing unit on the basis of the deterioration-reducing water distribution plan.

A first and a second static-pressure gas bearings supporting a rod at two locations in the axial direction in the non-contact manner are provided, in which the first static-pressure gas bearing is fixedly supported by a bearing housing, while the second static-pressure gas bearing is supported capable of displacement through a movable support mechanism. And this movable support mechanism has an actuator and suppresses contact of the rod with the static-pressure gas bearings by displacing the shaft center of the second static-pressure gas bearing with respect to the first static-pressure gas bearing by this actuator according to a load acting on the rod.

A tire condition detecting device according to the present invention includes: an electronic component including a sensor configured to detect a tire condition; and a casing configured to house the electronic component. The casing includes a casing main body configured to house the electronic component and having an opening surface formed thereon, and a lid unit configured to cover the opening surface. An inside of the casing main body having the opening surface covered by the lid unit is filled with a sealant. Accordingly, tire conditions such as inner pressure and temperature of a tire can be surely detected and a breakdown of an electronic component can be prevented even in an environment where water content such as a coolant is injected in the tire.

A display device includes a display configured to display a deterioration degree of a secondary battery and a controller. The controller is configured to control the display such that the display does not display the deterioration degree when the deterioration degree is lower than a first level, or configured to control the display such that the display does not display the deterioration degree when the deterioration degree is higher than a second level that is higher than the first level.

The present invention relates to a composition for prevention and treatment of kidney diseases comprising one or more effective component(s) of a PAR-2 activating agent which is able to activate PAR-2 and a pharmaceutically acceptable carrier. The present invention further relates to a method for prevention and treatment of kidney diseases comprising administration of a composition for prevention and treatment of kidney diseases containing a PAR-2 activating agent which is able to activate PAR-2 to patients suffering from kidney diseases, and also relates to the use of a PAR-2 activating agent which is able to activate PAR-2 for the manufacture of a composition for prevention and treatment of kidney diseases. The present invention furthermore relates to a method for screening an effective ingredient for prevention and treatment of kidney diseases comprising screening of the activating action of the test substance to PAR-2.

When a hot water supply operation is started, a single mode is used in which hot water is output only from a second hot water supply circuit of a water heater, by cut-off of a flow path in a first hot water supply circuit of a space-heating water heater by a cut-off mechanism. When a load imposed by hot water supply by the second hot water supply circuit increases during the hot water supply operation in the single mode, the cut-off mechanism is opened to start hot water output from the first hot water supply circuit and a hot water supply operation in a parallel mode is performed in which hot water is output from both of the first hot water supply circuit and the second hot water supply circuit.

In a power storage apparatus, for storing DC electric power, which is configured by connecting in series a plurality of modules each including a plurality of cells connected with one another, by providing two first switches at the input portion and at the output portion of the power storage apparatus and a second switch, in series with the modules, at a connection position where the modules are connected, the voltage to ground in the apparatus is lowered.

In a power storage apparatus, for storing DC electric power, which is configured by connecting in series a plurality of modules each including a plurality of cells connected with one another, by providing two first switches at the input portion and at the output portion of the power storage apparatus and a second switch, in series with the modules, at a connection position where the modules are connected, the voltage to ground in the apparatus is lowered.

A liquid ejection apparatus comprises a plurality of piezoelectric element units, which can be driven to eject liquid by changing a drive voltage, and a control device. The control device may calculate an accumulated time for each of the piezoelectric element units. The accumulated times may be a time that a respective piezoelectric element unit is in a driven state. The control device may also identify a first piezoelectric element unit having a maximum accumulated time and a second piezoelectric element unit having a minimum accumulated time from among the piezoelectric element units. The control device may reduce the drive voltage applied to one or more of the piezoelectric element units that are not in the driven state to a lower voltage, when the control device determines that the difference between the maximum accumulated time and the minimum accumulated time is less than a predetermined time.

Treating or preventing degeneration or destruction of articular cartilage and / or subchondral bone in the affected joint of a mammal is accomplished by administering a compound of formula (I), wherein the variables have the meanings given in the present description. A preferred compound of formula (I) is formula (II). This treatment ameliorates, diminishes, actively treats, reverses or prevents any injury, damage or loss of articular cartilage or subchondral bone subsequent to said early stage of said degeneration.

A liquid ejection apparatus comprises a plurality of piezoelectric element units, which can be driven to eject liquid by changing a drive voltage, and a control device. The control device may calculate an accumulated time for each of the piezoelectric element units. The accumulated times may be a time that a respective piezoelectric element unit is in a driven state. The control device may also identify a first piezoelectric element unit having a maximum accumulated time and a second piezoelectric element unit having a minimum accumulated time from among the piezoelectric element units. The control device may reduce the drive voltage applied to one or more of the piezoelectric element units that are not in the driven state to a lower voltage, when the control device determines that the difference between the maximum accumulated time and the minimum accumulated time is less than a predetermined time.