5results about How to "Improve hemostatic efficiency" patented technology

The application discloses a contact type laser scalpel convenient for speed control, and relates to the technical field of laser scalpel, which comprises a joint, a scalpel head arranged at the bottom end of the joint, and support assemblies symmetrically arranged on the two sides of the scalpel head; the support assembly comprises a spreading part, the spreading part is arranged in an inclined mode, the distance between the two spreading parts gradually decreases in the vertical upward direction, and the top end of the spreading part is hinged to the joint; the bottom end of the spreading part is in contact with human tissue S, and when the scalpel head is pushed down, the bottom ends of the two spreading parts gradually move away to push the wrinkled human tissue S flat. Two inclined spreading parts are symmetrically arranged on the two sides of the scalpel head, when the scalpel head is pushed down, the downward movement of the scalpel head can drive the bottom ends of the two spreading parts to gradually move away, so that the wrinkled human tissue S can be pushed flat, the bleeding part buried in the wrinkles is exposed, hemostasis is facilitated, the whole hemostasis process is short, the speed can be conveniently controlled, and the actual hemostasis efficiency is improved.

This invention proposes a visual human tissue rotary cutting device and its shell opening and closing control method, belonging to the field of shell medical device technology. The visual human tissue rotary cutting device includes a scalpel sheath, a blade, a ductoscope, an electrocoagulation hemostatic needle, a sampling chamber, and a puncture shell. The scalpel sheath is capable of axial feeding movement. The blade is installed in the scalpel sheath. The ductoscope is fixedly installed on the outer wall of the scalpel sheath. The electrocoagulation hemostatic needle is installed on the outer wall of the scalpel sheath and located on the opposite side of the ductoscope. The sampling chamber is connected to the scalpel sheath and an external vacuum device. The puncture shell includes a first half-shell and a second half-shell, which can be connected at their tail ends and open at their front ends, forming a bullet shape when combined. The lesion tissue is removed by rotating the blade, which completes axial cutting with the axial feeding of the scalpel sheath. The ductoscope provides the surgeon with a surgical field, which improves surgical accuracy and reduces recurrence. The electrocoagulation hemostatic needle is used to handle large-scale active bleeding.

This invention discloses a puncture positioning device for oncology, relating to the field of medical device technology. It includes a puncture needle assembly, a self-sealing assembly, a drug injection mechanism, and a disposable locator. The puncture needle assembly comprises a puncture needle tube and a puncture needle core. The puncture needle tube has a hollow structure, and the puncture needle core slidably passes through the inner wall of the puncture needle tube. The front end of the puncture needle tube has a puncture tip for easy penetration of human tissue. The self-sealing assembly includes an elastic sealing ring fixedly connected to the surface of the puncture needle tube. This invention, by setting an elastic sealing ring and a sliding sleeve on the surface of the puncture needle tube, allows the sliding sleeve to slide along the axial direction of the puncture needle tube. When the puncture needle penetrates the target tissue, it pushes the sliding sleeve forward, and a movable push rod compresses the elastic sealing ring, causing it to expand radially. This allows the edge of the elastic sealing ring to make close contact with the tissue wall, achieving closure of the needle tract and effectively reducing the risk of pneumothorax and bleeding.

The invention discloses composite hemostatic gauze cured by an ionic cross-linked network and a preparation method of the composite hemostatic gauze, and relates to the technical field of biomedical materials and biological medicine manufacturing, and the preparation method of the composite hemostatic gauze cured by the ionic cross-linked network comprises the following steps: preparing a base material: taking a chitosan non-woven fabric as the base material; preparing sizing liquid; padding and sizing are conducted, specifically, a chitosan non-woven fabric base material is soaked in the sizing liquid to be subjected to padding and sizing treatment; pre-drying and sizing: pre-drying the sized chitosan non-woven fabric base material obtained in the padding and sizing step; in-situ cross-linking enhancement: immersing the pre-dried chitosan non-woven fabric base material obtained in the pre-drying and shaping step into a cross-linking solution containing metal ions for cross-linking reaction; and post-processing. The kaolin particles can be physically embedded on the chitosan non-woven fabric base material through the ionic cross-linked network, so that the falling rate of the kaolin is reduced, and the use risk of the composite hemostatic gauze is reduced.

This invention belongs to the field of genetic engineering technology, specifically relating to a modular tandem repeat recombinant type III collagen with high platelet adhesion and its applications. The amino acid sequence of the recombinant type III collagen includes repeating units, with ≥3 repeating units; functional modules are inserted within each repeating unit. This invention integrates multiple discrete platelet-binding sites in type III collagen, designs a tandem repeat structure of different modular sequences (≥3 repeating units), optimizes spatial synergy, optimizes the gene sequence using codon bias, efficiently expresses the gene through a Pichia pastoris expression system, and obtains a high-purity product after purification. The recombinant type III collagen prepared by this invention exhibits good biocompatibility and can significantly promote erythrocyte and platelet adhesion; it can be widely used in wound repair, hemostatic materials, and tissue engineering.