The invention relates to vehicle-mounted communication multimedia equipment with an interface capable being customized by a user. The multimedia equipment comprises a main control unit, a power supply processing unit, a signal detection unit, a communication positioning unit, an interface unit, a Bluetooth/WIFI (wireless fidelity) communication unit and a man-machine interaction unit, wherein the power supply processing unit can provide various voltage grades, and can provide electric power for different modules or equipment, in addition, whether the electric power is supplied to different modules or equipment or not in different time periods can be controlled, and particularly, the equipment is also provided with an interface customization module used for controlling a screen of the multimedia equipment to work in different UI (user interface) formats according to the selection of a driver. The multimedia equipment has the advantages that the multi-option voltage sources are provided, in addition, the power supply can be saved, and in addition, the excellent man-machine interaction experience is realized.