The invention relates to an activation system based on a high-power battery, which belongs to the technical field of battery design on bullets; including a first motor pump battery, a second motor pump battery, a first small battery, a control system, a third motor pump battery, and a fourth motor pump battery and the second small battery; wherein, the control system is arranged in the equipment cabin of the aircraft; the first motor pump battery, the second motor pump battery and the first small battery are arranged in the front cabin of the aircraft; the third motor pump battery, the fourth The motor pump battery and the second small battery are arranged in the accessory compartment of the aircraft; wherein, the first small battery is provided with a first pyrotechnic device; the second small battery is provided with a second pyrotechnic device; when the power of the battery is relatively large At this time, the present invention adopts the method of matching a small battery, by sending the activation sequence of the small battery, so as to achieve the purpose of activating the high-power battery. The sequence number of the control system can be saved, the activation power supply current can be reduced, and it is also safe and reliable.