47 results about "Metallo enzyme" patented technology

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

The present disclosure describes compounds having agricultural fungicidal activity.

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

A stable composition preferably a refreshing drink for accelerating degradation of alcohol and acetaldehyde in the body, comprises synergistic combination of caffeine, herbs and fructose. Preferably, the composition comprises, Caffeine, Guaranà caffeine, Yerba Matè, Eleutherococcus senticous, Panax ginseng, ginger, Glycyrrhiza glabra (Liquorice Root), fructose and additional ingredients (sugars, flavourings, colourings, vitamins, stabilisers, whole fruit powder and the like), and optionally ginkgo biloba.

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

The invention provides a hydrogen production nano-device, a production method thereof, and a hydrogen production method thereof. The hydrogen production nano-device comprises metal nano-particles, a photoinduced electron donor, alpha-helical peptides and organic metalloenzyme. The hydrogen production nano-device can use renewable solar energy to realize efficient and pollution-free hydrogen generation, all raw materials used in the invention have very good environment endophilicity and no pollution, and the macroscopic dipole moment characteristic of the alpha-helical peptides is used to improve the unidirectional electron delivery efficiency and improve the hydrogen yield, so the problems of environment pollution and energy consumption of present hydrogen production methods are effectively solved.

An organic polyamine 1[bis(3-aminopropyl) amino]-2-propanol, that is, G9H23N3O, its preparing process and its application as chemical intermediate in preparing chelating agent, corrosion inhibitor, resin solidifying agent and catalyst and researching metallic enzyme are disclosed.

The invention discloses a functional fiber including protein, which comprises protein, high molecular polymer, and metalloenzyme, wherein, protein is A deals, high molecular polymer is B deals, and metalloenzyme is C deals of total amount, so, 1<=A<=67, 10 D01F 8 / 10 D01F 8 / 02 0 13 3 2004 / 4 / 27 1690260 2005 / 11 / 2 1297698 2007 / 1 / 31 2007 / 1 / 31 2007 / 1 / 31 Li Guanqi Henan 457000 Li Guanqi zhang chaolin 41109

The invention belongs to the field of artificial metalloenzyme, and discloses an efficient azo red dye decolorized enzyme and a preparation method and application thereof. According to the azo red dyedecolorized enzyme, myoglobin having the function of transporting oxygen is used as a protein molecule design framework, tyrosine is introduced to the 43rd site near the active center of myoglobin hemachrome, tryptophan is introduced to the 138th site, arginine is introduced to the 67th site, three-point mutant protein F43Y / F138W / T67R Mb is obtained, and the amino acid sequence is as shown in SEQID NO.1. The azo red dye decolorized enzyme disclosed by the invention can degrade azo red dye molecules under low hydrogen peroxide concentration and neutral condition so that decolourizing effects can be achieved; and the azo red dye decolorized enzyme can be widely applied to pollution control of industrial dye wastewater, and a method which is easy to implement, efficient and harmless to environment is provided for degradation of azo type dyes. The preparation method of the azo red dye decolorized enzyme is simple to operate, and is suitable for large-scale industrialization production.

A method of generating an antibody which inhibits a metalloenzyme is disclosed. The method comprises immunizing a subject with:(i) a synthetic zinc mimicry compound having structural and electronic properties similar to a catalytic domain of the metalloenzyme; and(ii) the metalloenzyme,Antibodies generated by this method are also disclosed as well as uses thereof.

Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

The present invention provides for a genetically modified host cell capable of producing an unnatural compound, such as terpenoid, comprising a P450 enzyme comprising an artificial cofactor, and the host cell is capable of uptaking the artificial cofactor by comprising a heterologous heme transport transmembrane protein, or homologue thereof.

The invention discloses an iris lacteal heavy metal ATP enzyme transport protein I1HMA2 as well as an encoding gene and application thereof. Cloning is carried out for the first time to obtain the encoding gene (SEQ ID No: 1) of the iris lacteal heavy metal ATP enzyme transport protein I1HMA2, the gene I1HMA2 can be used for strengthening the tolerance or the enrichment capacity of plants to cadmium or improving the transport capacity of the cadmium in the plants, and thus the remediation efficiency of the plants to soil cadmium pollution is improved. Transgenic plants with the cadmium resistance and strong enrichment capacity are prepared by utilizing a gene engineering technology to be capable of growing in the cadmium polluted environment, so that the iris lacteal heavy metal ATP enzyme transport protein I1HMA2 as well as the encoding gene and the application thereof provide a new thought of cultivating efficient cadmium enrichment transgenic plants, have an important application prospect in the aspects of improving the soil cadmium pollution remediation efficiency and the ecological environment and provide a new way and technological support for remediation of heavy metal polluted soil.

The invention belongs to the field of manual metalloenzyme and discloses high-efficiency decolorizing peroxidase and a preparation method and application thereof. According to the decolorizing peroxidase disclosed by the invention, myohemoglobin with an oxygen carrying function is utilized as protein molecules to design a framework, tyrosine is introduced to a 43 site near the heme active center of the myohemoglobin, and tryptophan is introduced to a 138 site; meanwhile, tryptophan is introduced to an 88 site at the periphery of the heme active center to obtain three-point mutant protein, andan amino acid sequence of the three-point mutant protein is shown as SEQ ID NO.1. According to the decolorizing peroxidase disclosed by the invention, a catalytic conversion number is improved, and dependence on hydrogen peroxide is reduced; the preparation method of the decolorizing peroxidase has the advantages of simpleness in operation and suitability for large-scale industrial production. Experiments show that the decolorizing peroxidase disclosed by the invention can degrade dye molecules under low-concentration hydrogen peroxide and within several seconds to achieve a decolorizing effect, a catalytic efficiency is increased by 130% compared with that of two-point mutant protein, and the decolorizing peroxidase can be widely applied to pollution treatment of industrial dye wastewater.