The invention discloses a closed-loop
percutaneous spinal cord electrical stimulation analgesia
system and method based on physiological feedback, and belongs to the field of noninvasive electrical stimulation analgesia technologies and stimulation control systems thereof. The
system comprises an
electrode patch, a flexible substrate of which is provided with at least one pair of
electrode units in an integrated manner, and the
electrode patch is used for being attached to a corresponding
spinal cord segment area of the
body surface of a subject; the physiological
signal acquisition module is used for acquiring a multi-
modal physiological
signal of a subject in real time; the stimulator is electrically connected with the electrode patch and used for generating and outputting electrical stimulation signals to at least one pair of electrode units of the electrode patch; the control module is connected with the physiological
signal acquisition module and the stimulator and is used for evaluating the pain state of the subject based on the physiological signals acquired by the physiological
signal acquisition module; and according to the
evaluation result, generating a control instruction to perform closed-loop adjustment on the output state of the stimulator. According to the
system, objective feedback is introduced, adaptability is improved, noninvasive individualization is achieved, operation is easy and convenient, and closed-loop
automatic control over monitoring, analysis and adjustment is achieved.