58 results about "Potassium benzoate" patented technology

Novel antimicrobial products and methods of making and using the same are shown, whereby the products can be used in the same or greater percentages as conventional microbial growth inhibitors without imparting an off-flavor, taste, color or odor to the products in which they are used. The antimicrobial products are formed by reacting azodicarbonamide or an ammonia gas with a compound selected from the group consisting of benzoic acid, sodium benzoate, calcium benzoate, potassium benzoate, acetic acid, sodium diacetate, paraben, niacin, calcium acetate, calcium diacetate, citric acid, lactic acid, fumaric acid, sorbic acid, sodium sorbate, calcium sorbate, potassium sorbate, propionic acid, sodium propionate, calcium propionate, potassium propionate and mixtures thereof. In one embodiment, the product is prepared by placing a layer of azodicarbonamide on a substrate and covering the layer with a gas permeable separator. The antimicrobial compound is then added on top of the separator, and the combination is heated to form the final product. In another embodiment, the product is prepared by exposing the antimicrobial compound to an ammonia gas. The ammonia gas reacts with free acids in the antimicrobial compound to convert the free acids into ammonium salts, thereby eliminating off-flavor and off-odor of the resulting antimicrobial product. The antimicrobial products prepared according to the present invention are suitable for use in foodstuffs, sanitation products, cosmetics, pharmaceuticals, and so forth.

The invention discloses a fire retardant containing a styrene structure and phosphorus and nitrogen elements. The fire retardant is obtained by reacting dialkyl phosphite with 4-aminostyrene and carbon tetrachloride in the presence of a catalyst, wherein the catalyst is a compound of an organic base and an inorganic base; the organic base catalyst is pyridine, triethylamine, diethylamine, triethanolamine, diethanolamine, aniline, tetrabutyl ammonium hydroxide or tetraethyl ammonium hydroxide, while the inorganic base catalyst is sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate, sodium bicarbonate, potassium bicarbonate, sodium benzoate or potassium benzoate; the mol ratio of the organic base to 4-aminostyrene is (3-1): 1 and the mol ratio of the inorganic base to 4-aminostyrene is (1.1-1): 1. Due to the existence of the styrene structure in the molecule, the fire retardant monomer is easy to have a polymerization reaction with active double bonds such as styrene and ethylene; in the meantime, due to the existence of phosphorus and nitrogen fire-retarding elements, the material is provided with fire resistance; carbon tetrachloride is used as a solvent in the synthesis process, so that the reaction is convenient to operate and high in yield; industrial production of the fire retardant is easy to realize.

The invention relates to a preparation method for telbivudine, which pertains to the technical field of organic chemical engineering and comprises the following technical steps: (1) 2'-deoxidized-beta-D-thymine nucleoside is taken as a raw material and anhydrous pyridine is taken as a solvent; the raw material and the solvent react with p-toluenesulfonyl chloride at the temperature of minus 5 DEG C to 0 DEG C; then centrifugalization and drying are carried out, and 3, 5-di-O-P- toluenesulfonyl chloride-beta-D-thymine nucleoside is obtained; (2) DMF is taken as a solvent, and the 3, 5-di-O-P- toluenesulfonyl chloride-beta-D-thymine nucleoside reacts with potassium benzoate at the temperature of minus 70 DEG C to 100 DEG C; configuration inversion and evaporation concentration are carried out, thus obtaining 3, 5-di-O- benzoyl-beta-L-thymine nucleoside; (3) hydrolysis is carried out on the 3, 5-di-O- benzoyl-beta-L-thymine nucleoside by using amino methanol, and 2'-deoxidized-beta-L-thymine nucleoside is obtained, thus obtaining the target object telbivudine. The preparation method has simple technique and short synthesizing route greatly reduces synthesizing time and production cost; in addition, the varieties of the solvents used are few, and the dosage of the solvents is greatly reduced, thereby being beneficial to environmental protection and safety in production and remarkably increasing comprehensive benefit compared with the prior art.

The invention discloses salts prepared from 2-(1-acyloxy-n-amyl)benzoic acid and basic amino acid or aminoguanidine, a preparation method thereof, a medicinal preparation containing the salts, and application of the salts to preparing of medicines used for preventing or treating ischemic cardiovascular and cerebral vascular diseases, resisting thrombus and relieving cardio-cerebral circulatory disturbance. A compound not only has good water solubility, aqueous solution stability and pharmacokinetics performance, but also has strong activity for resisting platelet aggregation, resisting thrombus, resisting cerebral ischemia and protecting nerves, the effect is superior to that of (S)-butylphthalide and (R / S)-2-(1-hydroxy-n-amyl)potassium benzoate salt (PHPB), acute toxicity of the compoundto mouse intravenous injection dosing is remarkably lower than that of butylphthalide and PHPB, the inhibition ratio of the compound to an hERG potassium channel of a CHO-hERG cell is lower than thatof the (S)-butylphthalide, and a result of a bacterial reverse mutation test (Ames test) is negative.

The invention discloses an ecology-simulated freshness-retaining method of ginseng and American ginseng, which is characterized in comprising the steps of: adding 3% of saccharose and 0.1% of potassium benzoate into MS major element solution; soaking a cotton paper with the solution to be made into a nutrition paper; packing the rootlets and the fibrils of the O3-sterilized fresh ginseng or American ginseng with the nutrition paper; covering a PE freshness-retaining internal bag out of the package part of the nutrition paper; putting the packed ginseng or American ginseng into a PE freshness-retaining external bag; vacuating the external bag; aerating mixed gas of 2-3% of 02, 3-4% of CO2 and 95-93% of N2; and sealing the external freshness-retaining bag, and refrigerating under the environment of 0-2 DEG C. The method uses O3 sterilization to prevent the fresh ginseng from rotting and deteriorating, and the freshness-retaining bags simulate the ecological environment of the dormant state of the ginseng or the American ginseng to lead the fibrils not to be withered and yellow, and the color and luster, the freshness and the hardness of the whole ginseng not to be changed, therefore, the freshness-retaining time is more than 6 months. The method is simple in operation and is convenient in mass production.

The invention discloses a colla corii asini, rock candy and snow pear cream and a preparation method thereof, belongs to a cream preparation of a traditional Chinese medicine, and particularly relates to a health-care medicine containing colla corii asini. The colla corii asini, rock candy and snow pear cream is prepared by following raw materials in parts by weight: 25 parts of rock candy, 60 parts of snow pear blocks, 5 parts of bulbus fritilariae, 5 parts of fructus momordicae, 5 parts of colla corii asini and 0.1 part of potassium benzoate. In the medicine, fructus momordicae, bulbus fritilariae and snow pears which have cold and cool properties are combined with colla corii asini, so that strengths are highlighted to make up weakness, the mutual assistance effect of drug matching of the traditional medicine is achieved, and the complementary curative effect is achieved; therefore, the prepared colla corii asini, rock candy and snow pear cream has the double effects of harmonizing stomach, moistening lung, relieving cough, reducing sputum, invigorating spleen-stomach, replenishing qi, and nourishing the blood and hemoslasis.

A method of treating antimicrobial products, dairy products, pharmaceutical products and other products having offensive tastes or odors to remove the off-odors and off-tastes from the products. The method involves exposing a selected commercial grade product that contains a small amount of free acid impurities to an ammonia gas. The ammonia gas reacts with the free acid impurities to convert the free acids into ammonium salts, thereby reducing or eliminating the off-flavor and off-odor of the product. The products to be treated include antimicrobial products selected from the group consisting of sodium benzoate, calcium benzoate, potassium benzoate, sodium diacetate, paraben, niacin, calcium acetate, calcium diacetate, sodium sorbate, calcium sorbate, potassium sorbate, sodium propionate, calcium propionate, potassium propionate and mixtures thereof; dairy products selected from the group consisting of casein, whey, skim milk powder, and calostrum; pharmaceutical products selected from the group consisting of acetaminiphen, aspirin, ibuprophen, dextromethorphan hydrobromide, guaejenesin, paracetamol, and sodium erythorbate; and various other products selected from the group consisting of butylate hydroxy tolulene, polydextrose powder, sodium acid sulfate, and sodium diacetate. The common characteristic of the commercial grades of each of these products is that they contain a small amount of free acid impurities that react favorably with ammonia gas.

The invention discloses a soaking solution for osmanthus fragrans cuttings. The soaking solution is prepared from the following components in parts by weight: 6 to 9 parts of capelin roe, 4 to 7 parts of osmanthus fragrans, 3 to 6 parts of kelp, 9 to 11 parts of fibrous root of fistular onion, 1 to 3 parts of sodium bromoethanesulphonate, 0.8 to 1.0 part of alliin, 2 to 3 parts of potassium benzoate and 30 to 40 parts of traditional Chinese medicinal liquid. The soaking solution for the osmanthus fragrans cuttings provided by the invention can effectively promote rooting of cuttings, promotes division and differentiation of plant cells, increases stress resistance of branches, and can accelerate the rooting rate of osmanthus fragrans branches, so good genetic stability of the osmanthus fragrans branches is guaranteed. The soaking solution provided by the invention has long shelf life and can be repeatedly used, so the cost is saved, and the environment is protected at the same time; and significances of popularization and application are achieved.