The invention relates to a lower limb rehabilitation training system based on a multi-position electric wheelchair. The lower limb rehabilitation training system is provided with a wheelchair frame, a standing mechanism, a lying mechanism and a lower limb training mechanism are arranged above the wheelchair frame, a running mechanism is arranged below the wheelchair frame, the standing mechanism and the lower limb training mechanism are rotationally connected with the wheelchair frame respectively, and the lying mechanism is rotationally connected with the standing mechanism, thereby realizing active training, passive training, weight loss training and balance training of a patient while standing, lying and seating. A wheelchair control and virtual reality training mechanism is arranged above the wheelchair frame, and the wheelchair control and virtual reality training mechanism is connected with the standing mechanism, the lying mechanism, the lower limb training mechanism and the running mechanism respectively under control, thereby realizing running as well as virtual reality-based multi-position lower limb training in seating, standing and lying ways.